Anti-BTG2/PC3 抗体 (ab85051)
Key features and details
- Rabbit polyclonal to BTG2/PC3
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-BTG2/PC3 antibody
BTG2/PC3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to BTG2/PC3 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human BTG2/PC3 (C terminal). A 15 amino acid synthetic peptide from the C-terminal residues.
Database link: NM_006763 -
ポジティブ･コントロール
- WB: HepG2 whole cell lysate (ab7900). IHC-P: Human fetal colon tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Lyophilized:Reconstitute in 200ul sterile H2O. -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.02% Sodium azide
Constituent: 2% BSA -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab85051の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (1) |
1/200 - 1/1000. Detects a band of approximately 18 kDa (predicted molecular weight: 18 kDa).
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| IHC-P |
1/100 - 1/500.
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| 特記事項 |
|---|
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WB
1/200 - 1/1000. Detects a band of approximately 18 kDa (predicted molecular weight: 18 kDa). |
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IHC-P
1/100 - 1/500. |
ターゲット情報
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機能
Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Anti-proliferative protein. Modulates transcription regulation mediated by ESR1. Involved in neurite outgrowth. -
配列類似性
Belongs to the BTG family. - Information by UniProt
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参照データベース
- Entrez Gene: 7832 Human
- Omim: 601597 Human
- SwissProt: P78543 Human
- Unigene: 519162 Human
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別名
- B cell translocation gene 2 antibody
- BTG family member 2 antibody
- Btg2 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BTG2/PC3 antibody (ab85051)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human fetal colon tissue labelling BTG2/PC3 with ab85051 at a dilution of 1/100.
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Western blot - Anti-BTG2/PC3 antibody (ab85051)Anti-BTG2/PC3 antibody (ab85051) at 1/250 dilution + HepG2 cell lysates
Predicted band size: 18 kDa
Observed band size: 18 kDa
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (8)
ab85051 は 8 報の論文で使用されています。
- Li X et al. miR-365 secreted from M2 Macrophage-derived extracellular vesicles promotes pancreatic ductal adenocarcinoma progression through the BTG2/FAK/AKT axis. J Cell Mol Med 25:4671-4683 (2021). PubMed: 33811437
- Li S et al. LINC01089 inhibits the progression of cervical cancer via inhibiting miR-27a-3p and increasing BTG2. J Gene Med 23:e3280 (2021). PubMed: 33025678
- Qu L et al. The miR-146b-5p promotes Ewing's sarcoma cells progression via suppressing the expression of BTG2. Sci Prog 104:368504211002043 (2021). PubMed: 33844600
- Li B et al. MicroRNA-934 facilitates cell proliferation, migration, invasion and angiogenesis in colorectal cancer by targeting B-cell translocation gene 2. Bioengineered 12:9507-9519 (2021). PubMed: 34699325
- Shang D et al. Pancreatic cancer cell-derived exosomal microRNA-27a promotes angiogenesis of human microvascular endothelial cells in pancreatic cancer via BTG2. J Cell Mol Med 24:588-604 (2020). PubMed: 31724333
- Hu D et al. Icariside II protects cardiomyocytes from hypoxia-induced injury by upregulating the miR-7-5p/BTG2 axis and activating the PI3K/Akt signaling pathway. Int J Mol Med 46:1453-1465 (2020). PubMed: 32945347
- Huang L et al. CircRNA_000864 Upregulates B-cell Translocation Gene 2 Expression and Represses Migration and Invasion in Pancreatic Cancer Cells by Binding to miR-361-3p. Front Oncol 10:547942 (2020). PubMed: 33425718
- Jiang H et al. PRMT5 promotes cell proliferation by inhibiting BTG2 expression via the ERK signaling pathway in hepatocellular carcinoma. Cancer Med 7:869-882 (2018). WB, IHC-P . PubMed: 29441724