Anti-BOLA3 抗体 (ab185339)
Key features and details
- Rabbit polyclonal to BOLA3
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-BOLA3 antibody
BOLA3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to BOLA3 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat
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免疫原
Recombinant fragment corresponding to BOLA3 aa 1 to the C-terminus.
Database link: Q53S33 -
ポジティブ･コントロール
- Human kidney tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab185339の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 特記事項 |
|---|
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IHC-P
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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組織特異性
Widely expressed. -
関連疾患
Defects in BOLA3 are the cause of multiple mitochondrial dysfunctions syndrome type 2 (MMDS2) [MIM:614299]. A severe disorder of systemic energy metabolism, resulting in weakness, respiratory failure, lack of neurologic development, lactic acidosis, hyperglycinemia and early death. Some patients show failure to thrive, pulmonary hypertension, hypotonia and irritability. Biochemical features include severe combined deficiency of the 2-oxoacid dehydrogenases, defective lipoic acid synthesis and reduction in activity of mitochondrial respiratory chain complexes. -
配列類似性
Belongs to the bolA/yrbA family. -
細胞内局在
Secreted. Could be secreted via a non-classical export pathway. - Information by UniProt
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参照データベース
- Entrez Gene: 388962 Human
- Entrez Gene: 297388 Rat
- SwissProt: Q53S33 Human
- SwissProt: Q8CEI1 Mouse
- Unigene: 61472 Human
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別名
- BolA-like protein 3 antibody
- BOLA3 antibody
- BOLA3_HUMAN antibody
- MMDS2 antibody
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BOLA3 antibody (ab185339)
Immunohistochemistry analysis of Human kidney tissue labeling BOLA3 with ab185339 at 1/200 dilution.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab185339 は 1 報の論文で使用されています。
- Wang D et al. Prognostic Values of BolA Family Member Expression in Hepatocellular Carcinoma. Biomed Res Int 2022:8360481 (2022). PubMed: 36017386