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AB155010

Anti-BNIP3L/NIX 抗体

Anti-BNIP3L/NIX antibody

  • JP Deleterious:医薬用外劇物

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(1 Publication)

Rabbit Polyclonal BNIP3L/NIX antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human BNIP3L aa 50-200.

別名を表示する

BNIP3A, BNIP3H, NIX, BNIP3L, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like, Adenovirus E1B19K-binding protein B5, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A, NIP3-like protein X, NIP3L

2 Images
Western blot - Anti-BNIP3L/NIX antibody (AB155010)
  • WB

Supplier Data

Western blot - Anti-BNIP3L/NIX antibody (AB155010)

Samples were separated by 10 % SDS.

All lanes:

Western blot - Anti-BNIP3L/NIX antibody (ab155010) at 1/1000 dilution

Lane 1:

Untreated HeLa whole cell extracts at 30 µg

Lane 2:

Treated HeLa whole cell extracts at 30 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 24 kDa

false

Immunocytochemistry/ Immunofluorescence - Anti-BNIP3L/NIX antibody (AB155010)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-BNIP3L/NIX antibody (AB155010)

Immunofluorescent analysis of methanol-fixed HeLa cells labeling BNIP3L/NIX with ab155010 antibody at 1/200 dilution. Bottom figure : staining merged with DNA probe (Hoechst 33342).

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Mouse, Human

アプリケーション

IHC-P, ICC/IF, WB

applications

免疫原

Synthetic Peptide within Human BNIP3L aa 50-200. The exact immunogen used to generate this antibody is proprietary information.

O60238

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Reactivity data

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下記製品もご検討ください

AB109414

Anti-BNIP3L/NIX antibody [EPR4033]

5
1 Reviews
製品ページを見る
こちらの製品も推奨する理由

私たちは、より高品質な製品をお届けするために、製品構成を常に改善しています。今回ご紹介する代替製品は、性能の向上、使いやすさや利便性の向上、またはより早くお届けできる点などを踏まえて選定しています。

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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
バッファー組成
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP : in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
See full target information BNIP3L
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Cell death & disease 11:251 PubMed32312970

2020

Drp1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-, BAX-, and GSH- pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Chenyang Duan,Lei Kuang,Xinming Xiang,Jie Zhang,Yu Zhu,Yue Wu,Qingguang Yan,Liangming Liu,Tao Li
View all publications
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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
保証に関する詳細については利用規約をご確認ください。
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