Anti-Blood Group A Antigen 抗体 [HE-193] (ab2521)
Key features and details
- Mouse monoclonal [HE-193] to Blood Group A Antigen
- Suitable for: IHC-P, Agglutination
- Reacts with: Human
- Isotype: IgM
製品の概要
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製品名
Anti-Blood Group A Antigen antibody [HE-193]
Blood Group A Antigen 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [HE-193] to Blood Group A Antigen -
由来種
Mouse -
特異性
This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssman antigen. -
アプリケーション
適用あり: IHC-P, Agglutinationmore details -
種交差性
交差種: Human -
免疫原
Mixture of erythrocytes of blood group A1 and glycoprotein fraction isolated from the saliva of secretors with blood group A.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Constituent: Tissue culture supernatant -
Concentration information loading...
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精製度
Tissue culture supernatant -
特記事項(精製)
Concentrated by ultrafiltration (100 kDa cut-off). Actual immunoglobulin concentration not determined. -
ポリ/モノ
モノクローナル -
クローン名
HE-193 -
ミエローマ
unknown -
アイソタイプ
IgM -
軽鎖の種類
unknown -
研究分野
関連製品
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Compatible Secondaries
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab2521の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use at an assay dependent concentration.
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Agglutination |
Use at an assay dependent concentration.
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特記事項 |
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IHC-P
Use at an assay dependent concentration. |
Agglutination
Use at an assay dependent concentration. |
ターゲット情報
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関連性
Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens. -
細胞内局在
Cell Membrane -
参照データベース
- Entrez Gene: 28 Human
データシートおよび資料
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Datasheet download
参考文献 (4)
ab2521 は 4 報の論文で使用されています。
- Säljö K et al. Characterization of Glycosphingolipids in the Human Parathyroid and Thyroid Glands. Int J Mol Sci 22:N/A (2021). PubMed: 34208903
- Li C et al. Association between the ABO blood group and primary knee osteoarthritis: A case-control study. J Orthop Translat 21:129-135 (2020). PubMed: 32309138
- Johansson MM et al. Characterization of moose intestinal glycosphingolipids. Glycoconj J 32:393-412 (2015). PubMed: 26104834
- Nemec M et al. Murine monoclonal antibodies to human A erythrocytes: differential reactivity with N-acetyl-D-galactosamine. Vox Sang 52:125-8 (1987). PubMed: 2440181