Anti-Blood Group A Antigen 抗体 [9A] (ab20131)
Key features and details
- Mouse monoclonal [9A] to Blood Group A Antigen
- Suitable for: ELISA, IP
- Reacts with: Human
- Isotype: IgG3
製品の概要
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製品名
Anti-Blood Group A Antigen antibody [9A]
Blood Group A Antigen 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [9A] to Blood Group A Antigen -
由来種
Mouse -
特異性
ab20131 cross reacts with EGF receptor in A431 cells only due to glycosylation defects in these cells which reveals otherwise cryptic sugar structures. -
アプリケーション
適用あり: ELISA, IPmore details -
種交差性
交差種: Human -
免疫原
Tissue, cells or virus corresponding to Human Blood Group A Antigen. A431 cells (human vulval squamous carcinoma cell line)
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
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精製度
Protein A/G purified -
ポリ/モノ
モノクローナル -
クローン名
9A -
ミエローマ
P3-x63-Ag8 -
アイソタイプ
IgG3 -
軽鎖の種類
unknown -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab20131の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
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特記事項 |
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ELISA
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
ターゲット情報
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関連性
Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens. -
細胞内局在
Cell Membrane -
参照データベース
- Entrez Gene: 28 Human
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab20131 は 4 報の論文で使用されています。
- Chauwa A et al. Maternal and Infant Histo-Blood Group Antigen (HBGA) Profiles and Their Influence on Oral Rotavirus Vaccine (RotarixTM) Immunogenicity among Infants in Zambia. Vaccines (Basel) 11:N/A (2023). PubMed: 37631871
- Fischer MB et al. Surface Plasmon Resonance Analysis Shows an IgG-Isotype-Specific Defect in ABO Blood Group Antibody Formation in Patients with Common Variable Immunodeficiency. Front Immunol 6:211 (2015). PubMed: 25999949
- Gullick WJ & Lemoine NR 'EGF receptor' antibody 29.1.1. J Pathol 162:275-6 (1990). PubMed: 2266467
- Parker PJ et al. Monoclonal antibodies against the human epidermal growth factor receptor from A431 cells. Isolation, characterization, and use in the purification of active epidermal growth factor receptor. J Biol Chem 259:9906-12 (1984). PubMed: 6086658