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AB15008

Anti-BLNK 抗体

Anti-BLNK antibody

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(10 Publications)

Rabbit Polyclonal BLNK antibody. Suitable for WB and reacts with Mouse samples. Cited in 10 publications. Immunogen corresponding to Recombinant Fragment Protein within Human BLNK.

別名を表示する

BASH, SLP65, BLNK, B-cell linker protein, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, SLP-65

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Mouse

アプリケーション

WB

applications

免疫原

Recombinant Fragment Protein within Human BLNK. The exact immunogen used to generate this antibody is proprietary information.

Q8WV28

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Proprietary technique
精製に関する特記事項
Purified from rabbit antisera by precipitation methods. Purity >95% by SDS-PAGE.
バッファー組成
pH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.
See full target information BLNK
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文献 (10)

Recent publications for all applications. Explore the full list and refine your search

PloS one 19:e0296989 PubMed38625901

2024

AM-18002, a derivative of natural anmindenol A, enhances radiosensitivity in mouse breast cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Da-Young Eum,Myeonggyo Jeong,Soon-Yong Park,Jisu Kim,Yunho Jin,Jeyun Jo,Jae-Woong Shim,Seoung Rak Lee,Seong-Joon Park,Kyu Heo,Hwayoung Yun,Yoo-Jin Choi

International journal of molecular sciences 24: PubMed36902094

2023

Overexpression of a Novel Noxo1 Mutant Increases Ros Production and Noxo1 Relocalisation.

Applications

Unspecified application

Species

Unspecified reactive species

Fatima-Zahra Benssouina,Fabrice Parat,Claude Villard,Ludovic Leloup,Françoise Garrouste,Jean-Marc Sabatier,Lotfi Ferhat,Hervé Kovacic

Cell death discovery 8:350 PubMed35927251

2022

M2-like tumor-associated macrophages transmit exosomal miR-27b-3p and maintain glioblastoma stem-like cell properties.

Applications

Unspecified application

Species

Unspecified reactive species

Guifang Zhao,Lijuan Ding,Hongquan Yu,Weiyao Wang,Huan Wang,Yao Hu,Lingsha Qin,Guangce Deng,Buqing Xie,Guofeng Li,Ling Qi

Cell death & disease 13:530 PubMed35668064

2022

STAT6 inhibits ferroptosis and alleviates acute lung injury via regulating P53/SLC7A11 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Youjing Yang,Yu Ma,Qianmin Li,Yi Ling,Yujia Zhou,Kaimiao Chu,Lian Xue,Shasha Tao

Bio-protocol 11:e4227 PubMed34909448

2021

Isolation of CD31 Bone Marrow Endothelial Cells (BMECs) from Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Alhaji Osman Smith,Seyram Yao Adzraku,Wen Ju,Jianlin Qiao,Kailin Xu,Lingyu Zeng

Frontiers in neuroscience 15:682036 PubMed34220437

2021

Seizures and Interictal Epileptiform Activity in the Rat Collagenase Model for Intracerebral Hemorrhage.

Applications

Unspecified application

Species

Unspecified reactive species

Charlotte Germonpré,Silke Proesmans,Charlotte Bouckaert,Mathieu Sprengers,Paul Boon,Robrecht Raedt,Veerle De Herdt

Frontiers in cell and developmental biology 9:643709 PubMed34109172

2021

Spatiotemporal Developmental Upregulation of Prestin Correlates With the Severity and Location of Cyclodextrin-Induced Outer Hair Cell Loss and Hearing Loss.

Applications

Unspecified application

Species

Unspecified reactive species

Dalian Ding,Haiyan Jiang,Senthilvelan Manohar,Xiaopeng Liu,Li Li,Guang-Di Chen,Richard Salvi

Stem cell research & therapy 12:267 PubMed33941266

2021

A novel strategy for isolation of mice bone marrow endothelial cells (BMECs).

Applications

Unspecified application

Species

Unspecified reactive species

Alhaji Osman Smith,Seyram Yao Adzraku,Wen Ju,Jianlin Qiao,Kailin Xu,Lingyu Zeng

Nature communications 10:1551 PubMed30948728

2019

The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo.

Applications

Unspecified application

Species

Unspecified reactive species

Kathrin Laue,Srivarsha Rajshekar,Abigail J Courtney,Zachary A Lewis,Mary G Goll

eLife 7: PubMed30484769

2018

Pericentromeric hypomethylation elicits an interferon response in an animal model of ICF syndrome.

Applications

Unspecified application

Species

Unspecified reactive species

Srivarsha Rajshekar,Jun Yao,Paige K Arnold,Sara G Payne,Yinwen Zhang,Teresa V Bowman,Robert J Schmitz,John R Edwards,Mary Goll
View all publications
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