Biotin Anti-MDC 抗体 (ab83129)
Key features and details
- Biotin Rabbit polyclonal to MDC
- Suitable for: WB, Sandwich ELISA
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG
製品の概要
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製品名
Biotin Anti-MDC antibody
MDC 一次抗体 製品一覧 -
製品の詳細
Biotin Rabbit polyclonal to MDC -
由来種
Rabbit -
標識
Biotin -
アプリケーション
適用あり: WB, Sandwich ELISAmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length Human MDC protein, highly pure (>98%).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Lyophilized:Reconstitute in sterile PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Constituent: PBS -
Concentration information loading... -
精製度
IgG fraction -
特記事項（精製）
ab83129 was purified by affinity chromatography and then biotinylated. Filter Sterilised. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab83129の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use at an assay dependent concentration. Predicted molecular weight: 11 kDa.
Detection limit for recombinant hMDC is 1.5 - 3 ng/lane, under either reducing or non-reducing conditions. |
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| Sandwich ELISA |
| 特記事項 |
|---|
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WB
Use at an assay dependent concentration. Predicted molecular weight: 11 kDa. Detection limit for recombinant hMDC is 1.5 - 3 ng/lane, under either reducing or non-reducing conditions. |
ターゲット情報
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機能
May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active. -
組織特異性
Highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus. Also found in lymph node, appendix, activated monocytes, resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. In lymph node expressed in a mature subset of Langerhans' cells (CD1a+ and CD83+). Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy. Expressed in atopic dermatitis, allergic contact dermatitis skin, and psoriasis, in both the epidermis and dermis. -
配列類似性
Belongs to the intercrine beta (chemokine CC) family. -
翻訳後修飾
The N-terminal processed forms MDC(3-69), MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 6367 Human
- Omim: 602957 Human
- SwissProt: O00626 Human
- Unigene: 534347 Human
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別名
- A 152E5.1 antibody
- ABCD 1 antibody
- ABCD1 antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (0)
ab83129 は論文での使用が確認できていません。
