Biotin Anti-Kappa light chain 抗体 (ab46807)
Key features and details
- Biotin Goat polyclonal to Kappa light chain
- Suitable for: ELISA
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
-
製品名
Biotin Anti-Kappa light chain antibody
Kappa light chain 一次抗体 製品一覧 -
製品の詳細
Biotin Goat polyclonal to Kappa light chain -
由来種
Goat -
標識
Biotin -
特異性
Reacts with human kappa light chains as demonstrated by ELISA and flow cytometry. Cross Absorption: Pooled human myeloma proteins with kappa light chains and mouse immunoglobulins. -
アプリケーション
適用あり: ELISAmore details -
種交差性
交差種: Human -
免疫原
Human myeloma proteins with kappa light chains
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. Store In the Dark. -
バッファー
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
Affinity chromatography on pooled human immunoglobulins with kappa light chains covalently linked to agarose. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab46807の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ELISA |
Use at an assay dependent concentration.
|
| 特記事項 |
|---|
|
ELISA
Use at an assay dependent concentration. |
ターゲット情報
-
関連性
Immunoglobulins belong to a group of related glyco proteins which make up 20% of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit; while, IgM is a pen tamer. IgA may also form polymers. Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83. -
細胞内局在
Cytoplasmic and Secreted -
参照データベース
- Entrez Gene: 28901 Human
- Entrez Gene: 3514 Human
- Omim: 147200 Human
- SwissProt: P01601 Human
- SwissProt: P01834 Human
-
別名
- HCAK 1 antibody
- HCAK1 antibody
- Ig kappa chain C region antibody
see all
画像
-
ELISA - Biotin Anti-Kappa light chain antibody (ab46807)
ELISA plate was coated with purified human IgGκ, IgMκ, IgAκ, IgGκ, IgMκ, and IgAκ. Immunoglobulins were detected with serially diluted ab46807 followed by Streptavidin-HRP.
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (0)
ab46807 は論文での使用が確認できていません。