Biotin Anti-Interferon gamma 抗体 (ab83136)
Key features and details
- Biotin Rabbit polyclonal to Interferon gamma
- Suitable for: Sandwich ELISA, WB
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG
製品の概要
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製品名
Biotin Anti-Interferon gamma antibody
Interferon gamma 一次抗体 製品一覧 -
製品の詳細
Biotin Rabbit polyclonal to Interferon gamma -
由来種
Rabbit -
標識
Biotin -
アプリケーション
適用あり: Sandwich ELISA, WBmore details -
種交差性
交差種: Mouse -
免疫原
Recombinant full length protein. This information is proprietary to Abcam and/or its suppliers.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Lyophilized:Centrifuge vial prior to opening. Reconstitute in sterile PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Constituent: PBS -
Concentration information loading... -
精製度
Protein A purified -
特記事項（精製）
ab83136 is sterile filtered. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab83136の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Sandwich ELISA |
Use at an assay dependent concentration.
This biotinylated polyclonal antibody, in conjunction with recommended pair as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant mIFN-gamma. Can be used as detection antibody when paired with ab9918. |
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| WB |
Use at an assay dependent concentration. Predicted molecular weight: 19 kDa.
The detection limit for recombinant murine Interferon gamma is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions. |
| 特記事項 |
|---|
|
Sandwich ELISA
Use at an assay dependent concentration. This biotinylated polyclonal antibody, in conjunction with recommended pair as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant mIFN-gamma. Can be used as detection antibody when paired with ab9918. |
|
WB
Use at an assay dependent concentration. Predicted molecular weight: 19 kDa. The detection limit for recombinant murine Interferon gamma is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions. |
ターゲット情報
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機能
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. -
組織特異性
Released primarily from activated T lymphocytes. -
関連疾患
In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis. -
配列類似性
Belongs to the type II (or gamma) interferon family. -
翻訳後修飾
Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 15978 Mouse
- SwissProt: P01580 Mouse
- Unigene: 240327 Mouse
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別名
- IF 1 antibody
- IFG antibody
- IFI antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab83136 は論文での使用が確認できていません。