Biotin Anti-IL-21 抗体 (ab77850)
Key features and details
- Biotin Rabbit polyclonal to IL-21
- Suitable for: WB, Sandwich ELISA
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG
製品の概要
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製品名
Biotin Anti-IL-21 antibody
IL-21 一次抗体 製品一覧 -
製品の詳細
Biotin Rabbit polyclonal to IL-21 -
由来種
Rabbit -
標識
Biotin -
アプリケーション
適用あり: WB, Sandwich ELISAmore details -
種交差性
交差種: Mouse -
免疫原
Recombinant full length protein corresponding to Mouse IL-21.
Database link: Q9ES17 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Lyophilized:Centrifuge vial prior to opening. Reconstitute in distilled water to a concentration of 0.1-1.0 mg/ml. -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Constituent: PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab77850の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use at an assay dependent concentration. Predicted molecular weight: 17 kDa.
Used in conjunction with compatible secondary reagents the detection limit for recombinant murine IL21 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing condition. |
|
| Sandwich ELISA |
Use at an assay dependent concentration.
Use as detection antibody with recommended pair. |
| 特記事項 |
|---|
|
WB
Use at an assay dependent concentration. Predicted molecular weight: 17 kDa. Used in conjunction with compatible secondary reagents the detection limit for recombinant murine IL21 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing condition. |
|
Sandwich ELISA
Use at an assay dependent concentration. Use as detection antibody with recommended pair. |
ターゲット情報
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機能
Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. -
組織特異性
Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. -
配列類似性
Belongs to the IL-15/IL-21 family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 60505 Mouse
- SwissProt: Q9ES17 Mouse
- Unigene: 157689 Mouse
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別名
- CVID11 antibody
- IL 21 antibody
- IL-21 antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (1)
ab77850 は 1 報の論文で使用されています。
- Cook KD et al. Correlation of In Vitro Kinetic Stability to Preclinical In Vivo Pharmacokinetics for a Panel of Anti-PD-1 Monoclonal Antibody Interleukin 21 Mutein Immunocytokines. Drug Metab Dispos 52:228-235 (2024). PubMed: 38135505
