Biotin Anti-Glucagon 抗体 (ab48287)
Key features and details
- Biotin Rabbit polyclonal to Glucagon
- Suitable for: ELISA, IHC-P, IP, RIA
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG
製品の概要
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製品名
Biotin Anti-Glucagon antibody
Glucagon 一次抗体 製品一覧 -
製品の詳細
Biotin Rabbit polyclonal to Glucagon -
由来種
Rabbit -
標識
Biotin -
アプリケーション
適用あり: ELISA, IHC-P, IP, RIAmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Sheep, Rabbit, Hamster, Cow, Dog, Pig, Xenopus laevis
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免疫原
Synthetic peptide corresponding to Human Glucagon aa 53-81 (internal sequence) conjugated to keyhole limpet haemocyanin.
Sequence:HSQGTFTSDYSKYLDSRRAQDFVQWLMNT
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.25% BSA -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab48287の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ELISA | (1) |
Use at an assay dependent concentration.
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| IHC-P |
Use at an assay dependent concentration.
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| IP |
Use at an assay dependent concentration.
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| RIA |
Use at an assay dependent concentration.
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| 特記事項 |
|---|
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ELISA
Use at an assay dependent concentration. |
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IHC-P
Use at an assay dependent concentration. |
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IP
Use at an assay dependent concentration. |
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RIA
Use at an assay dependent concentration. |
ターゲット情報
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関連性
Glucagon is a hormone that is secreted by alpha cells in the pancreas. Glucagon antagonizes insulin by converting glycogen to glucose in the liver and increasing blood sugar levels. Glucagon-like peptide 1 (GLP1), Glucagon-like peptide 2 (GLP2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are in the glucagons hormone family. GLP1 is a transmitter in the central nervous system that regulates feeding and drinking behavior. GLP2 stimulates intestinal epithelial growth. -
細胞内局在
Secreted -
参照データベース
- Entrez Gene: 280802 Cow
- Entrez Gene: 403571 Dog
- Entrez Gene: 2641 Human
- Entrez Gene: 14526 Mouse
- Entrez Gene: 397595 Pig
- Entrez Gene: 24952 Rat
- Omim: 138030 Human
- SwissProt: P01272 Cow
see all -
別名
- GCG antibody
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab48287 は 3 報の論文で使用されています。
- Renuse S et al. 13C15N: glucagon-based novel isotope dilution mass spectrometry method for measurement of glucagon metabolism in humans. Clin Proteomics 19:16 (2022). PubMed: 35590248
- Lee HY et al. Phosphatidylinositol 3-kinase-d controls endoplasmic reticulum membrane fluidity and permeability in fungus-induced allergic inflammation in mice. Br J Pharmacol 177:1556-1567 (2020). PubMed: 31713846
- Dalmas E et al. Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production. Immunity 47:928-942.e7 (2017). PubMed: 29166590