Biotin Anti-CD33 抗体 [HIM3-4] (ab21892)
![Flow Cytometry - Biotin Anti-CD33 antibody [HIM3-4] (ab21892)](https://www.abcam.co.jp/ps/products/21/ab21892/Images/ab21892-278888-anti-cd33-antibody-him3-4-biotin-flow-cytometry.jpg "Flow Cytometry - Biotin Anti-CD33 antibody [HIM3-4] (ab21892)")
Key features and details
- Biotin Mouse monoclonal [HIM3-4] to CD33
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG1
製品の概要
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製品名
Biotin Anti-CD33 antibody [HIM3-4]
CD33 一次抗体 製品一覧 -
製品の詳細
Biotin Mouse monoclonal [HIM3-4] to CD33 -
由来種
Mouse -
標識
Biotin -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Tissue, cells or virus corresponding to CD33. Human cell line NFMY-9s
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特記事項
The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.097% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
antibody purified. -
ポリ/モノ
モノクローナル -
クローン名
HIM3-4 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab21892の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use a concentration of 1 - 12 µg/ml.
ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
| 特記事項 |
|---|
|
Flow Cyt
Use a concentration of 1 - 12 µg/ml. ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro). -
組織特異性
Monocytic/myeloid lineage cells. -
配列類似性
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
ドメイン
Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases. -
翻訳後修飾
Phosphorylation of Tyr-340 is involved in binding to PTPN6 and PTPN11. Phosphorylation of Tyr-358 is involved in binding to PTPN6. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 945 Human
- Omim: 159590 Human
- SwissProt: P20138 Human
- Unigene: 83731 Human
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別名
- CD 33 antibody
- CD33 antibody
- CD33 antigen (gp67) antibody
see all
画像
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Flow Cytometry - Biotin Anti-CD33 antibody [HIM3-4] (ab21892)Flow Cytometry analysis of human peripheral blood cells labeling CD33 with Anti-CD33 antibody [HIM3-4] (Biotin) (ab21892).
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab21892 は論文での使用が確認できていません。