Biotin Anti-CD14 抗体 [MEM-15] (ab28118)
Key features and details
- Biotin Mouse monoclonal [MEM-15] to CD14
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG1
製品の概要
-
製品名
Biotin Anti-CD14 antibody [MEM-15]
CD14 一次抗体 製品一覧 -
製品の詳細
Biotin Mouse monoclonal [MEM-15] to CD14 -
由来種
Mouse -
標識
Biotin -
特異性
ab28118 recognises CD14 expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages. ab28118 also reacts with soluble forms of CD14 found in serum and in the urine of some nephrotic patients. -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Full length protein (Human): A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria.
-
ポジティブ・コントロール
- Flow Cyt: human peripheral blood cells
-
特記事項
The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.097% Sodium azide
Constituent: PBS -
Concentration information loading...
-
特記事項(精製)
The purified antibody is conjugated with biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin. -
ポリ/モノ
モノクローナル -
クローン名
MEM-15 -
アイソタイプ
IgG1 -
研究分野
関連製品
-
Alternative Versions
- PerCP/Cy5.5® Anti-CD14 antibody [MEM-15], prediluted (ab157312)
- APC/Cy7® Anti-CD14 antibody [MEM-15], prediluted (ab194805)
- PE/Cy5® Anti-CD14 antibody [MEM-15] (ab232910)
- PE/Cy7® Anti-CD14 antibody [MEM-15] (ab234214)
- Alexa Fluor® 700 Anti-CD14 antibody [MEM-15] (ab269326)
- PerCP Anti-CD14 antibody [MEM-15] (ab269327)
- FITC Anti-CD14 antibody [MEM-15] (ab28061)
- APC Anti-CD14 antibody [MEM-15] (ab60901)
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab28118の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use a concentration of 2 - 5 µg/ml.
ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
特記事項 |
---|
Flow Cyt
Use a concentration of 2 - 5 µg/ml. ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
ターゲット情報
-
機能
Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. -
組織特異性
Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages. -
配列類似性
Contains 11 LRR (leucine-rich) repeats. -
翻訳後修飾
N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan. -
細胞内局在
Cell membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 929 Human
- Omim: 158120 Human
- SwissProt: P08571 Human
- Unigene: 163867 Human
-
別名
- CD 14 antibody
- CD_antigen=CD14 antibody
- CD14 antibody
see all
画像
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (1)
ab28118 は 1 報の論文で使用されています。
- Horejsí V et al. Monoclonal antibodies against human leucocyte antigens. I. Antibodies against beta-2-microglobulin, immunoglobulin kappa light chains, HLA-DR-like antigens, T8 antigen, T1 antigen, a monocyte antigen, and a pan-leucocyte antigen. Folia Biol (Praha) 32:12-25 (1986). PubMed: 2422063