Biotin Anti-Carboxymethyl Lysine 抗体 (ab27685)
Key features and details
- Biotin Goat polyclonal to Carboxymethyl Lysine
- Suitable for: WB, ELISA
- Reacts with: Species independent
- Conjugation: Biotin
- Isotype: IgG
製品の概要
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製品名
Biotin Anti-Carboxymethyl Lysine antibody
Carboxymethyl Lysine 一次抗体 製品一覧 -
製品の詳細
Biotin Goat polyclonal to Carboxymethyl Lysine -
由来種
Goat -
標識
Biotin -
アプリケーション
適用あり: WB, ELISAmore details -
種交差性
交差種: Species independent -
免疫原
Carboxy methyl Lysine conjugated to KLH.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 6.5
Preservative: 0.02% Sodium azide
Constituents: 0.2% PBS, 0.0292% EDTA, 0.435% Sodium chloride, 30% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
This antibody was purified by Carboxy Methyl Lysine protein Sepharose affinity column. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab27685の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/2500 - 1/20000.
|
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| ELISA |
1/2500 - 1/20000.
|
| 特記事項 |
|---|
|
WB
1/2500 - 1/20000. |
|
ELISA
1/2500 - 1/20000. |
ターゲット情報
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関連性
N epsilon carboxymethyl lysine (CML or Carboxymethyl Lysine) is formed by the non enzymatic Schiff base reaction of glucose with proteins, followed by an Amadori rearrangement and oxidation that leaves only a carboxymethyl group attached to the lysine. The levels of CML adducts accumulate over time and have been used as an indicator of both serum glucose levels and oxidative protein damage. Elevated serum CML modified proteins have been associated with diabetes and may contribute to diabetic retinopathy, nephropathy and angiopathy. -
別名
- CML antibody
- N Epsilon (Carboxymethyl) Lysine antibody
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab27685 は 1 報の論文で使用されています。
- Menini S et al. The advanced glycation end-product N? -carboxymethyllysine promotes progression of pancreatic cancer: implications for diabetes-associated risk and its prevention. J Pathol 245:197-208 (2018). PubMed: 29533466