Anti-BFL-1/GRS 抗体 (ab45414)
Key features and details
- Rabbit polyclonal to BFL-1/GRS
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-BFL-1/GRS antibody
BFL-1/GRS 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to BFL-1/GRS -
由来種
Rabbit -
特異性
At least two isoforms of Bcl2A1/GRS are known to exist; this antibody will detect both isoforms.
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アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human BFL-1/GRS (N terminal). A 14 amino acid peptide from near the amino terminus of human BFL-1/GRS
Database link: Q16548 -
ポジティブ･コントロール
- WB: Human kidney tissue lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab45414の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 20 kDa).
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| 特記事項 |
|---|
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 20 kDa). |
ターゲット情報
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機能
Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection. -
組織特異性
Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies. -
配列類似性
Belongs to the Bcl-2 family. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 597 Human
- Omim: 601056 Human
- SwissProt: Q16548 Human
- Unigene: 227817 Human
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別名
- ACC 1 antibody
- ACC 2 antibody
- B2LA1_HUMAN antibody
see all
画像
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Western blot - Anti-BFL-1/GRS antibody (ab45414)Lane 1 : Anti-BFL-1/GRS antibody (ab45414) at 1 µg/ml
Lane 2 : Anti-BFL-1/GRS antibody (ab45414) at 2 µg/ml
All lanes : Human kidney tissue lysate
Predicted band size: 20 kDa
Observed band size: 20 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab45414 は 2 報の論文で使用されています。
- Liu F et al. UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma. Mol Oncol 15:3738-3752 (2021). PubMed: 34245648
- Gröschel M et al. Acute Noise Exposure Is Associated With Intrinsic Apoptosis in Murine Central Auditory Pathway. Front Neurosci 12:312 (2018). PubMed: 29867323