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リコンビナントRabMAb

Anti-Bcl6 抗体 [EPR11410] (ab171967)

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Western blot - Anti-Bcl6 antibody [EPR11410] (ab171967)
  • Anti-Bcl6 antibody [EPR11410] (ab171967)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR11410] to Bcl6
  • Suitable for: WB
  • Reacts with: Human

Conjugates logo Related conjugates and formulations

Carrier Free

製品の概要

  • 製品名

    Anti-Bcl6 antibody [EPR11410]
    Bcl6 一次抗体 製品一覧

  • 製品の詳細

    Rabbit monoclonal [EPR11410] to Bcl6

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: WBmore details
    適用なし: Flow Cyt,ICC/IF,IHC-P or IP

  • 種交差性

    交差種: Human

  • 免疫原

    Recombinant fragment within Human bcl-6. The exact sequence is proprietary.
    Database link: P41182

  • ポジティブ･コントロール

    • Ramos, Daudi and Raji cell lysates.

  • 特記事項

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab171967の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
WB
1/1000 - 1/5000. Predicted molecular weight: 79 kDa.
特記事項
WB
1/1000 - 1/5000. Predicted molecular weight: 79 kDa.
追加情報
Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.

ターゲット情報

  • 機能

    Transcriptional repressor which is required for germinal center formation and antibody affinity maturation. Probably plays an important role in lymphomagenesis.

  • 組織特異性

    Expressed in germinal center T and B cells and in primary immature dendritic cells.

  • 関連疾患

    Note=Chromosomal aberrations involving BCL6 may be a cause of B-cell non-Hodgkin lymphoma. Translocation t(3;14)(q27;q32); translocation t(3;22)(q27;q11) with immunoglobulin gene regions.
    Note=A chromosomal aberration involving BCL6 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with POU2AF1/OBF1.
    Note=A chromosomal aberration involving BCL6 may be a cause of lymphoma. Translocation t(3;4)(q27;p11) with ARHH/TTF.

  • 配列類似性

    Contains 1 BTB (POZ) domain.
    Contains 6 C2H2-type zinc fingers.

  • ドメイン

    The BTB domain mediates homodimerization. Its dimer interface mediates peptide binding such as to corepressors BCOR and NCOR2.

  • 翻訳後修飾

    Phosphorylated by MAPK1 in response to antigen receptor activation. Phosphorylation induces its degradation by ubiquitin/proteasome pathway.

  • 細胞内局在

    Nucleus.
  • Information by UniProt

  • 参照データベース

    • 別名

      • B cell CLL/lymphoma 6 antibody
      • B cell lymphoma 6 protein antibody
      • B-cell lymphoma 5 protein antibody
      • B-cell lymphoma 6 protein antibody
      • BCL 5 antibody
      • Bcl 6 antibody
      • BCL-5 antibody
      • BCL-6 antibody
      • BCL5 antibody
      • BCL6 antibody
      • BCL6_HUMAN antibody
      • BCL6A antibody
      • cys his2 zinc finger transcription factor antibody
      • cys-his2 zinc finger transcription factor antibody
      • LAZ 3 antibody
      • LAZ 3 protein antibody
      • LAZ3 antibody
      • Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3) antibody
      • Lymphoma associated zinc finger gene on chromosome 3 antibody
      • Protein LAZ-3 antibody
      • ZBTB 27 antibody
      • ZBTB27 antibody
      • Zinc finger and BTB domain containing protein 27 antibody
      • Zinc finger and BTB domain-containing protein 27 (ZBTB27) antibody
      • Zinc finger and BTB domain-containing protein 27 antibody
      • Zinc Finger Protein 51 (ZNF51) antibody
      • Zinc finger protein 51 antibody
      • zinc finger transcription factor BCL6S antibody
      • ZNF 51 antibody
      • ZNF51 antibody
      see all

    画像

    • Western blot - Anti-Bcl6 antibody [EPR11410] (ab171967)
      Western blot - Anti-Bcl6 antibody [EPR11410] (ab171967)
      All lanes : Anti-Bcl6 antibody [EPR11410] (ab171967) at 1/1000 dilution

      Lane 1 : Ramos cell lysate
      Lane 2 : Daudi cell lysate
      Lane 3 : Raji cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-rabbit HRP at 1/2000 dilution

      Developed using the ECL technique.

      Predicted band size: 79 kDa

    • Anti-Bcl6 antibody [EPR11410] (ab171967)
      Anti-Bcl6 antibody [EPR11410] (ab171967)

    参考文献 (0)

    ab171967 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab171967 は論文での使用が確認できていません。

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