Anti-BarX2 抗体 [BAR X2 8A7/1] (ab20128)
Key features and details
- Mouse monoclonal [BAR X2 8A7/1] to BarX2
- Suitable for: ELISA, IHC-P, ICC/IF, WB
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-BarX2 antibody [BAR X2 8A7/1] -
製品の詳細
Mouse monoclonal [BAR X2 8A7/1] to BarX2 -
由来種
Mouse -
アプリケーション
適用あり: ELISA, IHC-P, ICC/IF, WBmore details -
種交差性
交差種: Human -
免疫原
Fusion protein: MBP-tagged BarX2 (Human).
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特記事項
BarX2 is a tumour suppressor gene that encodes for a transcription factor known to regulate transcription of cell adhesion molecules in the mouse.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Constituent: PBS -
Concentration information loading... -
精製度
Protein A/G purified -
一次抗体 備考
BarX2 is a tumour suppressor gene that encodes for a transcription factor known to regulate transcription of cell adhesion molecules in the mouse. -
ポリ/モノ
モノクローナル -
クローン名
BAR X2 8A7/1 -
ミエローマ
Sp2/0-Ag14 -
アイソタイプ
IgG1 -
軽鎖の種類
unknown -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab20128の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ELISA |
Use at an assay dependent concentration.
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| IHC-P |
Use at an assay dependent concentration.
|
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| ICC/IF |
Use at an assay dependent concentration.
|
|
| WB | (1) |
Use at an assay dependent concentration.
|
| 特記事項 |
|---|
|
ELISA
Use at an assay dependent concentration. |
|
IHC-P
Use at an assay dependent concentration. |
|
ICC/IF
Use at an assay dependent concentration. |
|
WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system. May be involved in controlling adhesive processes in keratinizing epithelia. -
組織特異性
Highly expressed in adult salivary gland and at much lower levels in mammary gland, kidney and placenta. -
配列類似性
Belongs to the BAR homeobox family.
Contains 1 homeobox DNA-binding domain. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 8538 Human
- Omim: 604823 Human
- SwissProt: Q9UMQ3 Human
- Unigene: 591944 Human
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別名
- BarH like homeobox 2 antibody
- BarX 2 antibody
- BARX homeobox antibody
see all
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (1)
ab20128 は 1 報の論文で使用されています。
- Yang F et al. miR-942 promotes tumor migration, invasion, and angiogenesis by regulating EMT via BARX2 in non-small-cell lung cancer. J Cell Physiol 234:23596-23607 (2019). PubMed: 31236953
