Anti-BAFF-R 抗体 [EPR10914] (ab168389)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BAFF-R antibody [EPR10914] (ab168389)](https://www.abcam.co.jp/ps/products/168/ab168389/Images/ab168389-166695-anti-baff-r-antibody-epr10914-immunohistochemistry.gif "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BAFF-R antibody [EPR10914] (ab168389)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR10914] to BAFF-R
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-BAFF-R antibody [EPR10914]
BAFF-R 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR10914] to BAFF-R -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, ICC/IFmore details
適用なし: Flow Cyt,IP or WB -
種交差性
交差種: Human -
免疫原
Recombinant fragment corresponding to Human BAFF-R.
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ポジティブ･コントロール
- Human colon and tonsil tissues; Raji cells.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.5% BSA -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR10914 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab168389の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
1/250 - 1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
|
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| ICC/IF |
1/50 - 1/100.
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| 特記事項 |
|---|
|
IHC-P
1/250 - 1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
|
ICC/IF
1/50 - 1/100. |
ターゲット情報
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機能
B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. -
組織特異性
Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes. -
関連疾患
Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4) [MIM:613494]; also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. -
配列類似性
Contains 1 TNFR-Cys repeat. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 115650 Human
- Omim: 606269 Human
- SwissProt: Q96RJ3 Human
- Unigene: 344088 Human
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別名
- B cell activating factor receptor antibody
- B-cell-activating factor receptor antibody
- BAFF R antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BAFF-R antibody [EPR10914] (ab168389)
Immunohistochemical analysis of paraffin-embedded Human colon tissue labeling BAFF-R with ab168389 at 1/250 dilution.
Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BAFF-R antibody [EPR10914] (ab168389)](https://www.abcam.co.jp/ps/products/168/ab168389/Images/ab168389-166694-anti-baff-r-antibody-epr10914-immunohistochemistry.gif)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BAFF-R antibody [EPR10914] (ab168389)Immunohistochemical analysis of paraffin-embedded Human tonsil tissue labeling BAFF-R with ab168389 at 1/250 dilution.
Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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![Immunocytochemistry/ Immunofluorescence - Anti-BAFF-R antibody [EPR10914] (ab168389)](https://www.abcam.co.jp/ps/products/168/ab168389/Images/ab168389-166693-anti-baff-r-antibody-epr10914-immunofluorescence.gif)
Immunocytochemistry/ Immunofluorescence - Anti-BAFF-R antibody [EPR10914] (ab168389)Immunofluorescent analysis of Raji cells labeling BAFF-R with ab168389 at 1/50 dilution.
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![Anti-BAFF-R antibody [EPR10914] (ab168389)](https://www.abcam.co.jp/ps/products/168/ab168389/Images/ab168389-4-benefits-of-recombinant-antibodies.png)
Anti-BAFF-R antibody [EPR10914] (ab168389)
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab168389 は論文での使用が確認できていません。