Anti-B27 抗体 (ab168120)
Key features and details
- Mouse polyclonal to B27
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-B27 antibody -
製品の詳細
Mouse polyclonal to B27 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Chimpanzee
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免疫原
Recombinant full length protein within Human B27 aa 1-200. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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ポジティブ･コントロール
- B27 transfected 293T cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.4
Constituent: 99% PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab168120の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
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| WB | (1) |
Use a concentration of 1 µg/ml. Predicted molecular weight: 19 kDa.
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| 特記事項 |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 19 kDa. |
ターゲット情報
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機能
Required for MC2R expression in certain cell types, suggesting that it is involved in the processing, trafficking or function of MC2R. May be involved in the intracellular trafficking pathways in adipocyte cells. -
組織特異性
Expressed in adrenal cortex, testis, breast, thyroid, lymph node, ovary and fat. Expressed in adipose tissues. -
関連疾患
Defects in MRAP are the cause of glucocorticoid deficiency type 2 (GCCD2) [MIM:607398]; also known as familial glucocorticoid deficiency type 2 (FGD2). GCCD2 is an autosomal recessive disorder due to congenital insensitivity or resistance to adrenocorticotropin (ACTH). It is characterized by progressive primary adrenal insufficiency, without mineralocorticoid deficiency. -
細胞内局在
Cytoplasm > perinuclear region. Cytoplasm. Cell membrane. Endoplasmic reticulum. Concentrated at the perinuclear membrane region. Upon insulin stimulation, it is redistributed into spotty structures throughout the cytoplasm (By similarity). Localizes both to plasma membrane and endoplasmic reticulum. - Information by UniProt
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参照データベース
- Entrez Gene: 746245 Chimpanzee
- Entrez Gene: 56246 Human
- Omim: 609196 Human
- SwissProt: Q68UT4 Chimpanzee
- SwissProt: Q8TCY5 Human
- Unigene: 584940 Human
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別名
- B27 antibody
- C21orf61 antibody
- FALP antibody
see all
画像
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Western blot - Anti-B27 antibody (ab168120)All lanes : Anti-B27 antibody (ab168120) at 1 µg/ml
Lane 1 : B27 transfected 293T cell lysate
Lane 2 : Non-transfected lysate
Lysates/proteins at 15 µl per lane.
Secondary
All lanes : Goat Anti-Mouse IgG
Predicted band size: 19 kDa
データシートおよび資料
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Datasheet download
参考文献 (1)
ab168120 は 1 報の論文で使用されています。
- Nanba K et al. H295R expression of melanocortin 2 receptor accessory protein results in ACTH responsiveness. J Mol Endocrinol 56:69-76 (2016). PubMed: 26576642
