Anti-Avian Influenza A Hemagglutinin 抗体 (ab21297)
Key features and details
- Rabbit polyclonal to Avian Influenza A Hemagglutinin
- Suitable for: WB, ELISA
- Reacts with: Influenza A
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Avian Influenza A Hemagglutinin antibody
Avian Influenza A Hemagglutinin 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Avian Influenza A Hemagglutinin -
由来種
Rabbit -
特異性
Rabbit anti-Hemagglutinin (NT) protein polyclonal antibody was raised against a synthetic peptide corresponding to 15 amino acids at the amino terminus of the Hemagglutinin protein (Genbank accession no. AAT76166). Efforts were made to use relatively conserved regions of the viral sequence as the antigen. The antibody only recognizes the cleaved subunit not the full-length H5. -
アプリケーション
適用あり: WB, ELISAmore details -
種交差性
交差種: Influenza A -
免疫原
Synthetic peptide corresponding to 15 amino acids near the N terminus of the Hemagglutinin protein. (Peptide available as ab39772).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab21297の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 64 kDa.
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ELISA |
Use a concentration of 1 µg/ml.
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特記事項 |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 64 kDa. |
ELISA
Use a concentration of 1 µg/ml. |
ターゲット情報
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関連性
Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability. -
細胞内局在
Cell Membrane -
参照データベース
- GenBank: AGL44440 Influenza A
- SwissProt: P03453 Influenza A
- SwissProt: P16060 Influenza A
- SwissProt: P87506 Influenza A
- SwissProt: R4NN21 Influenza A
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別名
- HA1 antibody
- HA2 antibody
- Hemagglutinin antibody
see all
画像
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H5N1 HA Antibody (ab21297 at 1 µg/ml) specifically recognizes Avian Influenza A (H5N1), but not seasonal influenza A (H1N1), recombinant Hemagglutinin protein in ELISA.
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Western blot analysis of 5 ng (A) or 25 ng (B) of recombinant Hemagglutinin (HA1) using H5N1 Hemagglutinin antibody (ab21297 at 1 µg/ml.)
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (6)
ab21297 は 6 報の論文で使用されています。
- Lin SC et al. Glycan masking of hemagglutinin for adenovirus vector and recombinant protein immunizations elicits broadly neutralizing antibodies against H5N1 avian influenza viruses. PLoS One 9:e92822 (2014). WB . PubMed: 24671139
- Lin SC et al. Heterologous prime-boost immunization regimens using adenovirus vector and virus-like particles induce broadly neutralizing antibodies against H5N1 avian influenza viruses. Biotechnol J 8:1315-22 (2013). PubMed: 23813782
- Lin SC et al. Broader Neutralizing Antibodies against H5N1 Viruses Using Prime-Boost Immunization of Hyperglycosylated Hemagglutinin DNA and Virus-Like Particles. PLoS One 7:e39075 (2012). WB . PubMed: 22720032
- Pan YS et al. Construction and characterization of insect cell-derived influenza VLP: cell binding, fusion, and EGFP incorporation. J Biomed Biotechnol 2010:506363 (2010). WB . PubMed: 21197092
- Poon LL et al. Vaccinia virus-based multivalent H5N1 avian influenza vaccines adjuvanted with IL-15 confer sterile cross-clade protection in mice. J Immunol 182:3063-71 (2009). WB . PubMed: 19234203
- Guo Y et al. Analysis of hemagglutinin-mediated entry tropism of H5N1 avian influenza. Virol J 6:39 (2009). PubMed: 19341465