Anti-ATAD3A 抗体 (ab112572)
Key features and details
- Rabbit polyclonal to ATAD3A
- Suitable for: WB, ICC/IF, ICC
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-ATAD3A antibody
ATAD3A 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to ATAD3A -
由来種
Rabbit -
特異性
ab112572 is predicted to not cross-react with other ATAD protein family members. -
アプリケーション
適用あり: WB, ICC/IF, ICCmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human ATAD3A (N terminal). A 19 amino acid peptide corresponding to a region near the N terminal of Human ATAD3A.
Database link: Q9NVI7 -
ポジティブ･コントロール
- Daudi cell lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
ab112572 is purified by affinity chromatography purified via peptide column. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab112572の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 71 kDa.
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| ICC/IF |
Use a concentration of 20 µg/ml.
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| ICC |
Use a concentration of 20 µg/ml.
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| 特記事項 |
|---|
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 71 kDa. |
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ICC/IF
Use a concentration of 20 µg/ml. |
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ICC
Use a concentration of 20 µg/ml. |
ターゲット情報
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関連性
ATAD3A belongs to the AAA ATPase family. ATPases are a class of enzymes that catalyze the decomposition of adenosine triphosphate (ATP) into adenosine diphosphate (ADP) and a free phosphate ion. Two different isoforms obtained by alternative splicing, are known. -
細胞内局在
Mitochondrial -
参照データベース
- Entrez Gene: 55210 Human
- Omim: 612316 Human
- SwissProt: Q9NVI7 Human
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別名
- AAA-ATPase TOB3 antibody
- Atad3a antibody
- ATPase family AAA domain containing protein 3A antibody
see all
画像
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Immunocytochemistry/ Immunofluorescence - Anti-ATAD3A antibody (ab112572)Immunofluorescence of ATAD3A in Daudi cells with ab112572 at 20 ug/mL.
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Western blot - Anti-ATAD3A antibody (ab112572)Anti-ATAD3A antibody (ab112572) at 1 µg/ml + Daudi cell lysate at 15 µg
Predicted band size: 71 kDa -
Immunocytochemistry - Anti-ATAD3A antibody (ab112572)Immunocytochemistry of ATAD3A in Daudi cells with ab112572 at 20 ug/mL.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab112572 は 3 報の論文で使用されています。
- Zhao Y et al. ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models. Nat Commun 13:1121 (2022). PubMed: 35236834
- Zhao Y et al. ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects. Nat Commun 10:1371 (2019). PubMed: 30914652
- Betancourt A et al. Alterations in the rat serum proteome induced by prepubertal exposure to bisphenol a and genistein. J Proteome Res 13:1502-14 (2014). PubMed: 24552547