Anti-Apolipoprotein B 抗体 (ab31992)
Key features and details
- Rabbit polyclonal to Apolipoprotein B
- Suitable for: WB, Immunodiffusion
- Reacts with: Mouse, Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Apolipoprotein B antibody
Apolipoprotein B 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Apolipoprotein B -
由来種
Rabbit -
特異性
ab31992 recognizes Apolipoprotein B48 and B100, as these proteins are highly conserved. -
アプリケーション
適用あり: WB, Immunodiffusionmore details -
種交差性
交差種: Mouse, Human -
免疫原
SDS PAGE purified mouse Apolipoprotein B48 (very low density lipoprotein) from pooled mouse plasma.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
Preservative: 0.05% Sodium azide
Constituent: 40% Glycerol -
Concentration information loading... -
精製度
Whole antiserum -
特記事項（精製）
ab31992 is a heat inactivated neat serum. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab31992の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (2) |
Use at an assay dependent concentration.
|
| Immunodiffusion |
Use at an assay dependent concentration.
|
| 特記事項 |
|---|
|
WB
Use at an assay dependent concentration. |
|
Immunodiffusion
Use at an assay dependent concentration. |
ターゲット情報
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機能
Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. -
関連疾患
Hypobetalipoproteinemia, familial, 1
Familial ligand-defective apolipoprotein B-100
Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia. -
配列類似性
Contains 1 vitellogenin domain. -
翻訳後修飾
Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle. -
細胞内局在
Cytoplasm. Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 338 Human
- Entrez Gene: 238055 Mouse
- Omim: 107730 Human
- SwissProt: P04114 Human
- SwissProt: E9Q414 Mouse
- Unigene: 120759 Human
- Unigene: 221239 Mouse
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別名
- Apo B 100 antibody
- Apo B antibody
- Apo B-100 antibody
see all
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (14)
ab31992 は 14 報の論文で使用されています。
- Bond LM et al. Fitm2 is required for ER homeostasis and normal function of murine liver. J Biol Chem 299:103022 (2023). PubMed: 36805337
- Quiroz-Figueroa K et al. TRIB1 regulates LDL metabolism through CEBPα-mediated effects on the LDL receptor in hepatocytes. J Clin Invest 131:N/A (2021). PubMed: 34779419
- Hu PA et al. Bromelain Confers Protection against the Non-Alcoholic Fatty Liver Disease in Male C57bl/6 Mice. Nutrients 12:N/A (2020). PubMed: 32443556
- Burrello J et al. An extracellular vesicle epitope profile is associated with acute myocardial infarction. J Cell Mol Med 24:9945-9957 (2020). PubMed: 32666618
- Lassen S et al. Perilipin-2 is critical for efficient lipoprotein and hepatitis C virus particle production. J Cell Sci 132:N/A (2019). PubMed: 30559250