Anti-APG5L/ATG5 抗体 [ATG5/2101]
Anti-APG5L/ATG5 antibody [ATG5/2101]
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(4 Publications)
Mouse Monoclonal APG5L/ATG5 antibody. Suitable for WB, Protein Array, IHC-P and reacts with Human, Recombinant full length protein - Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Fragment Protein within Human ATG5 aa 1-150.
別名を表示する
APG5L, ASP, ATG5, Autophagy protein 5, APG5-like, Apoptosis-specific protein
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APG5L/ATG5 antibody [ATG5/2101] (AB238092)
Formalin-fixed, paraffin-embedded human brain tissue stained for APG5L/ATG5 using ab238092 at 2 μg/ml in immunohistochemical analysis.
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APG5L/ATG5 antibody [ATG5/2101] (AB238092)
Formalin-fixed, paraffin-embedded human endometrium tissue stained for APG5L/ATG5 using ab238092 at 2 μg/ml in immunohistochemical analysis.
- WB
Supplier Data
Western blot - Anti-APG5L/ATG5 antibody [ATG5/2101] (AB238092)
All lanes:
Western blot - Anti-APG5L/ATG5 antibody [ATG5/2101] (ab238092) at 2 µg/mL
Lane 1:
THP-1 (human monocytic leukemia cell line) cell lysate
Lane 2:
Human brain tissue lysate
Predicted band size: 32 kDa
false
- Protein Array
Supplier Data
Protein Array - Anti-APG5L/ATG5 antibody [ATG5/2101] (AB238092)
Analysis of Protein Array containing more than 19,000 full-length human proteins using ab238092.
Z- and S- Score : The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Reactivity data
出荷温度及び保存条件
製品の状態
精製方法
精製に関する特記事項
バッファー組成
出荷温度
短期保存期間
短期保存温度
長期保存温度
分注に関する情報
保管に関する情報
補足情報
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
ATG5 plays an important part in the cellular process of autophagy affecting the degradation and recycling of cellular components. It is a part of a complex with ATG12 and ATG16L1 which facilitates the membrane building of the autophagosome. This protein is important for maintaining cellular homeostasis allowing the removal of damaged proteins and organelles and is involved in responses to stress and starvation.
Pathways
ATG5 is an important component in the autophagy pathway and is involved in cellular maintenance processes. This pathway is vital for the regulation of cell growth and metabolism. ATG5 works closely with other autophagy-related proteins such as LC3. The ATG5-ATG12 complex helps in the lipidation of LC3 which is critical for autophagosome maturation connecting its function to the mTOR signaling pathway that regulates many cellular processes.
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文献 (4)
Recent publications for all applications. Explore the full list and refine your search
Molecular cancer therapeutics 24:1171-1185 PubMed40231599
2025
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Oxidative medicine and cellular longevity 2022:3504279 PubMed36062186
2022
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Bioengineered 12:10187-10198 PubMed34860641
2021
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Oncology reports 45:665-679 PubMed33416155
2021
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Unspecified reactive species
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