Anti-Apc4 抗体 (ab113364)
Key features and details
- Rabbit polyclonal to Apc4
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-Apc4 antibody
Apc4 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Apc4 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Rat
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免疫原
Synthetic peptide conjugated to KLH, corresponding to N terminal region of Human Apc4.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab113364の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 92 kDa.
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| IHC-P |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 特記事項 |
|---|
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 92 kDa. |
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IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. -
パスウェイ
Protein modification; protein ubiquitination. -
配列類似性
Belongs to the APC4 family. - Information by UniProt
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参照データベース
- Entrez Gene: 29945 Human
- Entrez Gene: 52206 Mouse
- Entrez Gene: 305420 Rat
- Omim: 606947 Human
- SwissProt: Q9UJX5 Human
- SwissProt: Q91W96 Mouse
- Unigene: 152173 Human
- Unigene: 272568 Mouse
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別名
- ANAPC 4 antibody
- anapc4 antibody
- Anaphase Promoting Complex Subunit 4 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Apc4 antibody (ab113364)ab113364, at 5µg/ml, staining Apc4 in Formalin-fixed, Paraffin-embedded Human Spleen tissue by Immunohistochemistry.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Apc4 antibody (ab113364)ab113364, at 5µg/ml, staining Apc4 in Formalin-fixed, Paraffin-embedded Human uterus tissue by Immunohistochemistry. -
Western blot - Anti-Apc4 antibody (ab113364)Lane 1 : Anti-Apc4 antibody (ab113364) at 1 µg/ml
Lane 2 : Anti-Apc4 antibody (ab113364) at 2 µg/ml
All lanes : Mouse liver tissue lysate
Predicted band size: 92 kDa
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab113364 は論文での使用が確認できていません。