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AB25486

APC Anti-IL-2 Receptor alpha 抗体 [7D4]

APC Anti-IL-2 Receptor alpha antibody [7D4]

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(4 Publications)

Anti-IL-2 Receptor alpha antibody [7D4] conjugated to APC - suitable for flow cytometry, and reacts with mouse samples. Clone [7D4] is a rat monoclonal antibody cited in 82 publications.

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別名を表示する

CD25, Il2r, Il2ra, Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, p55

1 Images
Flow Cytometry - APC Anti-IL-2 Receptor alpha antibody [7D4] (AB25486)
  • Flow Cyt

Supplier Data

Flow Cytometry - APC Anti-IL-2 Receptor alpha antibody [7D4] (AB25486)

Con-A stimulated BALB/c mouse splenocytes were stained with Rat Anti- Mouse CD25-APC (ab25486). The grey peak represents an isotype control. The purple peak represents the positive dataset.

Key facts

宿主種

Rat

クローン性

Monoclonal

クローン番号

7D4

アイソタイプ

IgM

軽鎖のタイプ

kappa

標識

APC

励起波長/蛍光波長

Ex: 650nm, Em: 660nm

キャリアフリー

No

交差種

Mouse

アプリケーション

Flow Cyt

applications

免疫原

Cell preparation containing Il2ra protein. The exact immunogen used to generate this antibody is proprietary information.

P01590

エピトープ

ab25486 reacts with an epitope between amino acids 125 and 212.

特異性

<p>ab25486 reacts with the low affinity alpha chain IL-2 receptor (IL-2Ralpha).</p>

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "0.2 µg for 10^6 Cells", "FlowCyt-species-notes": "<p></p>" } } }

出荷温度及び保存条件

製品の状態
Liquid
精製度
IgM fraction
バッファー組成
pH: 7.3 Preservative: 0.09% Sodium azide Constituents: PBS, 16% Sucrose
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
+4°C
保管に関する情報
Store in the dark

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

ターゲットの情報

Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.
See full target information Il2ra

文献 (4)

Recent publications for all applications. Explore the full list and refine your search

Journal of immunology (Baltimore, Md. : 1950) 185:956-66 PubMed20548032

2010

Synergistic antitumor effects of regulatory T cell blockade combined with pemetrexed in murine malignant mesothelioma.

Applications

Flow Cyt

Species

Mouse

Masaki Anraku,Tetsuzo Tagawa,Licun Wu,Zhihong Yun,Shaf Keshavjee,Li Zhang,Michael R Johnston,Marc de Perrot

Journal of immunology (Baltimore, Md. : 1950) 147:2970-7 PubMed1717581

1991

Structure-function study of the p55 subunit of murine IL-2 receptor by epitope mapping.

Applications

Unspecified application

Species

Unspecified reactive species

F Lorenzo,C Jaulin,N Vita,P Froussard,P Ferrara,D L Jankovic,J Theze

European journal of immunology 17:929-35 PubMed2440696

1987

Monoclonal antibodies identify three epitope clusters on the mouse p55 subunit of the interleukin 2 receptor: relationship to the interleukin 2-binding site.

Applications

Unspecified application

Species

Unspecified reactive species

J L Moreau,M Nabholz,T Diamantstein,T Malek,E Shevach,J Thèze

Journal of immunology (Baltimore, Md. : 1950) 133:1970-5 PubMed6206144

1984

The murine IL 2 receptor. I. Monoclonal antibodies that define distinct functional epitopes on activated T cells and react with activated B cells.

Applications

Unspecified application

Species

Unspecified reactive species

G Ortega,R J Robb,E M Shevach,T R Malek
View all publications

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