JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB272351

APC/Cy7® Anti-CD90 / Thy1 抗体 [5E10]

APC/Cy7® Anti-CD90 / Thy1 antibody [5E10]

5

(2 Reviews)

|

(2 Publications)

Anti-CD90 / Thy1 antibody [5E10] conjugated to APC/Cy7® - suitable for flow cytometry, and reacts with human samples. Clone [5E10] is a mouse monoclonal antibody and one of the most commonly used clones for flow cytometry.

Design your panel with our interactive flow cytometry panel builder. Click here.

別名を表示する

CD90, Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen, THY1

2 Images
Flow Cytometry - APC/Cy7® Anti-CD90 / Thy1 antibody [5E10] (AB272351)
  • Flow Cyt

Supplier Data

Flow Cytometry - APC/Cy7® Anti-CD90 / Thy1 antibody [5E10] (AB272351)

Flow cytometric analysis of Jurkat cells labeling CD90 with ab272351 at 4μl reagent per milion cells in 100 μl of cell suspension.

Flow Cytometry - APC/Cy7® Anti-CD90 / Thy1 antibody [5E10] (AB272351)
  • Flow Cyt

Supplier Data

Flow Cytometry - APC/Cy7® Anti-CD90 / Thy1 antibody [5E10] (AB272351)

Separation of Jurkat cells (Red) from SP2 cells (dashed) in flow cytometric analysis labeling CD90 using ab272351. (4 μl reagent per milion cells in 100 μl of cell suspension).

関連する標識済み抗体及び組成の異なる製品 (6)

  • 660 APC

    APC Anti-CD90 / Thy1 antibody [5E10]

  • 519 FITC

    FITC Anti-CD90 / Thy1 antibody [5E10]

  • 578 PE

    PE Anti-CD90 / Thy1 antibody [5E10]

  • 578 PE

    PE Anti-CD90 / Thy1 antibody [5E10]

  • 667 PE/Cy5®

    PE/Cy5® Anti-CD90 / Thy1 antibody [5E10]

  • 695 PerCP/Cy5.5®

    PerCP/Cy5.5® Anti-CD90 / Thy1 antibody [5E10]

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

5E10

アイソタイプ

IgG1

標識

APC/Cy7®

励起波長/蛍光波長

Ex: 650nm, Em: 785nm

キャリアフリー

No

交差種

Human

アプリケーション

Flow Cyt

applications

免疫原

Cell preparation containing THY1 protein. The exact immunogen used to generate this antibody is proprietary information.

P04216

style
left-column

組合せ製品

Assay Kits

AB285258

Mouse/Rat Thyroxine (T4) ELISA Kit

  • 0
  • 0
Primary Antibodies

AB200315

Alexa Fluor® 488 Anti-CD45 antibody [EP322Y]

RabMAb|Recombinant

Flow Cytometry (Intracellular) - Alexa Fluor® 488 Anti-CD45 antibody [EP322Y] (AB200315)

  • 0
  • 0
Primary Antibodies

AB195013

Alexa Fluor® 488 Anti-CD34 antibody [EP373Y]

RabMAb|Recombinant

Flow Cytometry (Intracellular) - Alexa Fluor® 488 Anti-CD34 antibody [EP373Y] (AB195013)

  • 5
  • 5
Primary Antibodies

AB318177

Alexa Fluor® 568 Anti-CD73 antibody [EPR28213-52]

Recombinant|RabMAb|KO Validated

Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 568 Anti-CD73 antibody [EPR28213-52] (AB318177)

  • 0
  • 0
Primary Antibodies

AB307399

Alexa Fluor® 488 Anti-CD105 antibody [EPR22811-18]

RabMAb|Recombinant

Flow Cytometry - Alexa Fluor® 488 Anti-CD105 antibody [EPR22811-18] (AB307399)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>" } } }
style
left-column

製品の詳細

This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.
style
left-column

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Size-exclusion chromatography
精製に関する特記事項
Purified from TCS.
バッファー組成
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
+4°C
保管に関する情報
Do Not Freeze
style
left-column

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

CD90 also known as Thy1 is a glycoprotein with a molecular mass of approximately 25-37 kDa. It is highly conserved across species and found on the surface of various cell types including fibroblasts neurons and endothelial cells. CD90 is expressed in these cells in tissues such as the brain thymus and lungs. Researchers use anti-CD90 antibodies for detection often in combination with CD90 FITC in immunofluorescence assays. CD90 serves as a useful cell marker particularly in identifying mesenchymal stem cells (MSCs).
Biological function summary

CD90 plays a role in cell-cell and cell-matrix interactions contributing to cellular adhesion migration and signal transduction. It functions as part of a complex involving integrins which mediate its interaction with the extracellular matrix. This protein also influences T-cell activation reflecting its importance in immune response regulation. Its presence aids in modulating response to injury and promoting tissue repair due to its association with stem and progenitor cells.

Pathways

CD90 engagement affects focal adhesion and MAPK signaling pathways. It interacts with integrins like αvβ3 and α5β1 influencing cell movement and proliferation processes. CD90 involvement in these pathways allows it to regulate responses important for cell survival and communication within various tissues. These interactions highlight the protein's role in maintaining cellular homeostasis and regulating physiological processes.

CD90 has associations with fibrosis and cancer. In fibrotic conditions CD90 expression affects fibroblast activity influencing tissue scarring in organs such as the liver and lungs. In cancer CD90 modifies tumor progression and metastasis by impacting cell adhesion and migration with connections to proteins like TGF-beta which further drive these processes. Understanding CD90 in disease contexts facilitates the development of therapeutic strategies aimed at modulating its activity.
style
left-column
style
left-column

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

ターゲットの情報

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
See full target information THY1
style
left-column

文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Advanced healthcare materials 12:e2202550 PubMed36527264

2022

Toward 3D Bioprinting of Osseous Tissue of Predefined Shape Using Single-Matrix Cell-Bioink Constructs.

Applications

Unspecified application

Species

Unspecified reactive species

Yawei Gu,Sebastien Pigeot,Lucas Ahrens,Fabian Tribukait-Riemenschneider,Melika Sarem,Francine Wolf,Andres García-García,Andrea Barbero,Ivan Martin,V Prasad Shastri

Journal of extracellular biology 1:e39 PubMed38939527

2022

Liver cancer cells with nuclear MET overexpression release translation regulatory protein-enriched extracellular vesicles exhibit metastasis promoting activity.

Applications

Unspecified application

Species

Unspecified reactive species

Sze Keong Tey,Samuel Wan Ki Wong,Cherlie Lot Sum Yeung,Jason Ying Ki Li,Xiaowen Mao,Clive Yik Sham Chung,Judy Wai Ping Yam
View all publications
style
left-column
style
left-column
style
right-column

Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com