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AB233298

APC/Cy7® Anti-CD4 抗体 [MEM241]

APC/Cy7® Anti-CD4 antibody [MEM-241]

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(2 Publications)

Anti-CD4 antibody [MEM-241] conjugated to APC/Cy7® - suitable for flow cytometry, and reacts with human samples. Clone [MEM-241] is a mouse monoclonal antibody cited in 8 publications.

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別名を表示する

CD4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3

3 Images
Flow Cytometry - APC/Cy7® Anti-CD4 antibody [MEM-241] (AB233298)
  • Flow Cyt

Supplier Data

Flow Cytometry - APC/Cy7® Anti-CD4 antibody [MEM-241] (AB233298)

Flow cytometric analysis of surface stained human peripheral blood cells, labeling CD4 with ab233298. Leukocyte gate.

Flow Cytometry - APC/Cy7® Anti-CD4 antibody [MEM-241] (AB233298)
  • Flow Cyt

Supplier Data

Flow Cytometry - APC/Cy7® Anti-CD4 antibody [MEM-241] (AB233298)

Flow cytometry surface staining pattern of human peripheral whole blood stained using ab233298 (concentration in sample 0.33 µg/ml).

Flow Cytometry - APC/Cy7® Anti-CD4 antibody [MEM-241] (AB233298)
  • Flow Cyt

Supplier Data

Flow Cytometry - APC/Cy7® Anti-CD4 antibody [MEM-241] (AB233298)

Flow cytometry surface staining pattern of human peripheral whole blood stained using ab233298 (concentration in sample 0.33 µg/ml).

関連する標識済み抗体及び組成の異なる製品 (7)

  • 660 APC

    APC Anti-CD4 antibody [MEM-241]

  • 723 Alexa Fluor® 700

    Alexa Fluor® 700 Anti-CD4 antibody [MEM-241]

  • Biotin

    Biotin Anti-CD4 antibody [MEM-241]

  • 519 FITC

    FITC Anti-CD4 antibody [MEM-241]

  • 578 PE

    PE Anti-CD4 antibody [MEM-241]

  • 778 PE/Cy7®

    PE/Cy7® Anti-CD4 antibody [MEM-241]

  • 675 PerCP

    PerCP Anti-CD4 antibody [MEM-241]

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

MEM-241

アイソタイプ

IgG1

軽鎖のタイプ

kappa

標識

APC/Cy7®

励起波長/蛍光波長

Ex: 650nm, Em: 785nm

キャリアフリー

No

交差種

Human

アプリケーション

Flow Cyt

applications

免疫原

Recombinant Fragment Protein within Human CD4. The exact immunogen used to generate this antibody is proprietary information.

P01730

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "4 µL for 10^6 Cells", "FlowCyt-species-notes": "<p>(or 100 μL whole blood)</p>" } } }

製品の詳細

This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Size-exclusion chromatography
精製に関する特記事項
The purified antibody is conjugated with tandem dye APC-Cy™7 under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
バッファー組成
pH: 7.4 Preservative: 0.0975% Sodium azide Constituents: PBS
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
+4°C
保管に関する情報
Store in the dark

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

ターゲットの情報

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule : peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.. (Microbial infection) Primary receptor for human immunodeficiency virus-1 (HIV-1) (PubMed : 12089508, PubMed : 16331979, PubMed : 2214026, PubMed : 9641677). Down-regulated by HIV-1 Vpu (PubMed : 17346169). Acts as a receptor for Human Herpes virus 7/HHV-7 (PubMed : 7909607).
See full target information CD4

文献 (2)

Recent publications for all applications. Explore the full list and refine your search

PloS one 19:e0310389 PubMed39292698

2024

Visfatin (NAMPT) expression in human placenta cells in normal and pathological conditions and its hormonal regulation in trophoblast JEG-3 cells.

Applications

Unspecified application

Species

Unspecified reactive species

Monika Dawid,Patrycja Kurowska,Piotr Pawlicki,Małgorzata Kotula-Balak,Tomasz Milewicz,Joelle Dupont,Agnieszka Rak

Immunity, inflammation and disease 10:e723 PubMed36301026

2022

Low serum level of 25-OH vitamin D relates to Th17 and treg changes in colorectal cancer patients.

Applications

Unspecified application

Species

Unspecified reactive species

Bai Chen,Liugen Jin
View all publications

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