AB25322

APC Anti-CD90 / Thy1 抗体 [G7]

Name: APC Anti-CD90 / Thy1 抗体 [G7] (ab25322) | Abcam
Brand: Abcam Limited
SKU: AB25322
Price: 45000 JPY
Availability: InStock

APC Anti-CD90 / Thy1 antibody [G7]

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(5 Publications)

Anti-CD90 / Thy1 antibody [G7] conjugated to APC - suitable for flow cytometry, and reacts with mouse samples. Clone [G7] is a rat monoclonal antibody cited in 75 publications.

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別名を表示する

CD90, Thy-1, Thy1, Thy-1 membrane glycoprotein, Thy-1 antigen

1 Images

Flow Cytometry - APC Anti-CD90 / Thy1 antibody [G7] (AB25322)

Flow Cyt

Unknown

Flow Cytometry - APC Anti-CD90 / Thy1 antibody [G7] (AB25322)

Flow cytometry analysis of BALB/c mouse splenocytes stained with Rat Anti-Mouse CD90-APC ab25322 (0.01 µg/10⁶cells) and Rat Anti-Mouse CD3 epsilon-FITC ab24948.

Key facts

宿主種

Rat

クローン性

Monoclonal

クローン番号

アイソタイプ

IgG2c

軽鎖のタイプ

kappa

標識

APC

励起波長/蛍光波長

Ex: 650nm, Em: 660nm

キャリアフリー

交差種

Mouse

アプリケーション

Flow Cyt

applications

エピトープ

ab25322 reacts with an epotpe located in the region A of CD90/Thy1.

特異性

ab25322 recognises Thy1.1 and Thy1.2 alloantigens.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "0.2 µg for 10^6 Cells", "FlowCyt-species-notes": "<p></p>" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification

バッファー組成

pH: 7.3 Preservative: 0.09% Sodium azide Constituents: PBS, 16% Sucrose

出荷温度

Blue Ice

短期保存温度

+4°C

長期保存温度

+4°C

保管に関する情報

Store in the dark

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

CD90 also known as Thy1 is a glycoprotein with a molecular mass of approximately 25-37 kDa. It is highly conserved across species and found on the surface of various cell types including fibroblasts neurons and endothelial cells. CD90 is expressed in these cells in tissues such as the brain thymus and lungs. Researchers use anti-CD90 antibodies for detection often in combination with CD90 FITC in immunofluorescence assays. CD90 serves as a useful cell marker particularly in identifying mesenchymal stem cells (MSCs).

Biological function summary

CD90 plays a role in cell-cell and cell-matrix interactions contributing to cellular adhesion migration and signal transduction. It functions as part of a complex involving integrins which mediate its interaction with the extracellular matrix. This protein also influences T-cell activation reflecting its importance in immune response regulation. Its presence aids in modulating response to injury and promoting tissue repair due to its association with stem and progenitor cells.

Pathways

CD90 engagement affects focal adhesion and MAPK signaling pathways. It interacts with integrins like αvβ3 and α5β1 influencing cell movement and proliferation processes. CD90 involvement in these pathways allows it to regulate responses important for cell survival and communication within various tissues. These interactions highlight the protein's role in maintaining cellular homeostasis and regulating physiological processes.

CD90 has associations with fibrosis and cancer. In fibrotic conditions CD90 expression affects fibroblast activity influencing tissue scarring in organs such as the liver and lungs. In cancer CD90 modifies tumor progression and metastasis by impacting cell adhesion and migration with connections to proteins like TGF-beta which further drive these processes. Understanding CD90 in disease contexts facilitates the development of therapeutic strategies aimed at modulating its activity.

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

See full target information Thy1

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文献 (5)

Recent publications for all applications. Explore the full list and refine your search

Journal of orthopaedic surgery and research 18:876 PubMed37980502

2023

BRD4 facilitates osteogenic differentiation of human bone marrow mesenchymal stem cells through WNT4/NF-κB pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Tao Ning,Huihui Guo,Mingming Ma,Zhengang Zha

Oxidative medicine and cellular longevity 2022:5772509 PubMed36105481

2022

Leukemia Inhibitory Factor Facilitates Self-Renewal and Differentiation and Attenuates Oxidative Stress of BMSCs by Activating PI3K/AKT Signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Youde Liang,Ruiping Zhou,Xin Liu,Lin You,Chang Chen,Xiaoling Ye,Wei Wei,Jie Liu,Jiawei Dai,Kaixiong Li,Xiangxiang Zhao

Cancer cell 39:1227-1244.e20 PubMed34297917

2021

Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity.

Applications

Unspecified application

Species

Unspecified reactive species

Colin Hutton,Felix Heider,Adrian Blanco-Gomez,Antonia Banyard,Alexander Kononov,Xiaohong Zhang,Saadia Karim,Viola Paulus-Hock,Dale Watt,Nina Steele,Samantha Kemp,Elizabeth K J Hogg,Joanna Kelly,Rene-Filip Jackstadt,Filipa Lopes,Matteo Menotti,Luke Chisholm,Angela Lamarca,Juan Valle,Owen J Sansom,Caroline Springer,Angeliki Malliri,Richard Marais,Marina Pasca di Magliano,Santiago Zelenay,Jennifer P Morton,Claus Jørgensen

Cell reports 35:109009 PubMed33882319

2021

Contextual cues from cancer cells govern cancer-associated fibroblast heterogeneity.

Applications

Unspecified application

Species

Unspecified reactive species

Neus Bota-Rabassedas,Priyam Banerjee,Yichi Niu,Wenjian Cao,Jiayi Luo,Yuanxin Xi,Xiaochao Tan,Kuanwei Sheng,Young-Ho Ahn,Sieun Lee,Edwin Roger Parra,Jaime Rodriguez-Canales,Jacob Albritton,Michael Weiger,Xin Liu,Hou-Fu Guo,Jiang Yu,B Leticia Rodriguez,Joshua J A Firestone,Barbara Mino,Chad J Creighton,Luisa M Solis,Pamela Villalobos,Maria Gabriela Raso,Daniel W Sazer,Don L Gibbons,William K Russell,Gregory D Longmore,Ignacio I Wistuba,Jing Wang,Harold A Chapman,Jordan S Miller,Chenghang Zong,Jonathan M Kurie

Journal of leukocyte biology 85:438-44 PubMed19056861

2008

Adenosine A2A receptors play an active role in mouse bone marrow-derived mesenchymal stem cell development.

Applications

Flow Cyt

Species

Mouse

Majid Katebi,Mansooreh Soleimani,Bruce N Cronstein

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

APC Anti-CD90 / Thy1 抗体 [G7]

APC Anti-CD90 / Thy1 antibody [G7]

Flow Cytometry - APC Anti-CD90 / Thy1 antibody [G7] (AB25322)

関連する標識済み抗体及び組成の異なる製品 (4)

Key facts

宿主種

クローン性

クローン番号

アイソタイプ

軽鎖のタイプ

標識

励起波長/蛍光波長

キャリアフリー

交差種

アプリケーション

エピトープ

特異性

代替製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

組合せ製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存温度

長期保存温度

保管に関する情報

補足情報

Biological function summary

Pathways

製品プロトコール

ターゲットの情報

文献 (5)

Abcam product promise