APC Anti-CD23 抗体 [2G8] (ab25457)
Key features and details
- APC Rat monoclonal [2G8] to CD23
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG2a
製品の概要
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製品名
APC Anti-CD23 antibody [2G8]
CD23 一次抗体 製品一覧 -
製品の詳細
APC Rat monoclonal [2G8] to CD23 -
由来種
Rat -
標識
APC. Ex: 645nm, Em: 660nm -
特異性
ab25457 recognises CD23 low affinity IgE Fc receptor. -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus corresponding to CD23. FcεR isolated from B cell lymphoma cell line M12.4.5
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Store In the Dark. -
バッファー
pH: 7.3
Preservative: 0.09% Sodium azide
Constituents: PBS, 16% Sucrose
Stabilising agent. -
Concentration information loading...
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精製度
Affinity purified -
ポリ/モノ
モノクローナル -
クローン名
2G8 -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab25457の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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Flow Cyt |
特記事項 |
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Note: ab25457 can be used for identification and enumeration of CD23+ cells by flow cytometry and for differentiation of B cell subpopulations by cell sorting.
IP: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能
This receptor has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). -
配列類似性
Contains 1 C-type lectin domain. -
翻訳後修飾
N- and O-glycosylated. -
細胞内局在
Cell membrane. Secreted. Also exists as a soluble excreted form. - Information by UniProt
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参照データベース
- Entrez Gene: 14128 Mouse
- SwissProt: P20693 Mouse
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別名
- Blast 2 antibody
- BLAST-2 antibody
- Blast2 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab25457 は 1 報の論文で使用されています。
- Hamel K et al. Suppression of Proteoglycan-Induced Arthritis by Anti-CD20 B Cell Depletion Therapy Is Mediated by Reduction in Autoantibodies and CD4+ T Cell Reactivity. J Immunol 180:4994-5003 (2008). Flow Cyt ; Mouse . PubMed: 18354225