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AB233256

APC Anti-Bone marrow stromal cell antigen 1 抗体 [SY11B5]

APC Anti-Bone marrow stromal cell antigen 1 antibody [SY11B5]

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(1 Publication)

Anti-Bone marrow stromal cell antigen 1 antibody [SY11B5] conjugated to APC - suitable for flow cytometry, and reacts with human samples. Clone [SY11B5] is a mouse monoclonal antibody cited in 2 publications.

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別名を表示する

CD157, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, ADP-ribosyl cyclase 2, Bone marrow stromal cell antigen 1, Cyclic ADP-ribose hydrolase 2, BST-1, cADPR hydrolase 2, BST1

1 Images
Flow Cytometry - APC Anti-Bone marrow stromal cell antigen 1 antibody [SY11B5] (AB233256)
  • Flow Cyt

Supplier Data

Flow Cytometry - APC Anti-Bone marrow stromal cell antigen 1 antibody [SY11B5] (AB233256)

Surface staining of human peripheral blood leukocytes with ab233256. Gated on leukocytes.

関連する標識済み抗体及び組成の異なる製品 (1)

  • Unconjugated

    Anti-Bone marrow stromal cell antigen 1 antibody [SY11B5]

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

SY11B5

アイソタイプ

IgG1

標識

APC

励起波長/蛍光波長

Ex: 650nm, Em: 660nm

キャリアフリー

No

交差種

Human, Primates

アプリケーション

Flow Cyt

applications

免疫原

Full Length Protein corresponding to Human BST1. The exact immunogen used to generate this antibody is proprietary information.

Q10588

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代替製品

Primary Antibodies

AB233455

FITC Anti-Bone marrow stromal cell antigen 1 antibody [SY11B5]

Flow Cytometry - FITC Anti-Bone marrow stromal cell antigen 1 antibody [SY11B5] (AB233455)

  • 0
  • 0
Primary Antibodies

AB235786

Anti-Bone marrow stromal cell antigen 1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Bone marrow stromal cell antigen 1 antibody (AB235786)

  • 0
  • 0
Primary Antibodies

AB137718

Anti-Bone marrow stromal cell antigen 1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Bone marrow stromal cell antigen 1 antibody (AB137718)

  • 0
  • 0

組合せ製品

Assay Kits

AB267623

Human CD157 ELISA kit

Sandwich ELISA - Human CD157 ELISA kit (AB267623)

  • 0
  • 0
Primary Antibodies

AB200315

Alexa Fluor® 488 Anti-CD45 antibody [EP322Y]

RabMAb|Recombinant

Flow Cytometry (Intracellular) - Alexa Fluor® 488 Anti-CD45 antibody [EP322Y] (AB200315)

  • 0
  • 0
Primary Antibodies

AB215912

Alexa Fluor® 647 Anti-CD31 antibody [JC/70A]

Immunocytochemistry - Alexa Fluor® 647 Anti-CD31 antibody [JC/70A] (AB215912)

  • 0
  • 1
Primary Antibodies

AB315961

Alexa Fluor® 488 Anti-CD90 / Thy1 antibody [EPR28145-53]

RabMAb|Recombinant

Flow Cytometry - Alexa Fluor® 488 Anti-CD90 / Thy1 antibody [EPR28145-53] (AB315961)

  • 0
  • 0
Primary Antibodies

AB310688

Alexa Fluor® 594 Anti-Glycophorin A antibody [EPR8200]

RabMAb|Recombinant

  • 0
  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "10 µL for 10^6 Cells", "FlowCyt-species-notes": "<p></p>" }, "Primates": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "10 µL for 10^6 Cells", "FlowCyt-species-notes": "<p></p>" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Size-exclusion chromatography
バッファー組成
pH: 7.4 Preservative: 0.0975% Sodium azide Constituents: PBS
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
+4°C
保管に関する情報
Store in the dark
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Bone marrow stromal cell antigen 1 (BST-1) also known as CD157 is a glycosylphosphatidylinositol-anchored protein with a molecular weight of approximately 38-42 kDa. You find BST-1 expression on the surface of various cell types especially within bone marrow stromal cells and cells of the immune system such as monocytes and macrophages. This protein functions as an ecto-enzyme with ADP-ribosyl cyclase activity and is part of the NADase enzyme family. Its mechanical role involves metabolizing extracellular NAD+ influencing cellular calcium signaling and energy metabolism.
Biological function summary

BST-1 contributes to the regulation of cellular interactions and immune responses. It participates in the organization of leukocyte trafficking and the formation of signal transduction cascades. BST-1 operates as a single protein but interacts with other membrane proteins to coordinate cellular communication. You can observe its function in processes like cell adhesion and migration impacting the immune surveillance and response systems.

Pathways

BST-1 plays a role in immune signaling and calcium-signaling pathways. In the immune system pathway it associates with molecules such as integrins to modulate leukocyte adhesion and transmigration. The calcium-signaling pathway is another key area where BST-1 interacts with intracellular proteins influencing various cellular targets and affecting metabolic processes critical for cell survival and proliferation.

Scientists have linked BST-1 to various conditions such as leukemia and chronic inflammation. Its expression levels often change in these diseases emphasizing its potential role in their progression. Researchers also explore the connection between BST-1 and other proteins like CD38 in the context of leukemia where both proteins might participate in cancer cell proliferation and survival. Understanding BST-1 in disease contexts provides insights into disease mechanisms and potential therapeutic strategies.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Catalyzes both the synthesis of cyclic ADP-beta-D-ribose (cADPR) from NAD(+), and its hydrolysis to ADP-D-ribose (ADPR) (PubMed : 7805847). Cyclic ADPR is known to serve as an endogenous second messenger that elicits calcium release from intracellular stores, and thus regulates the mobilization of intracellular calcium (Probable). May be involved in pre-B-cell growth (Probable).
See full target information BST1
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Acta biochimica et biophysica Sinica 56:1365-1372 PubMed38877781

2024

Hepatitis E virus infection upregulates ING5 expression and .

Applications

Unspecified application

Species

Unspecified reactive species

Wanqiu Zhao,Yueping Xia,Tengyuan Li,Huichan Liu,Guo Zhong,Dongxue Chen,Wenhai Yu,Yunlong Li,Fen Huang
View all publications
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