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AB196942

Anti-Annexin-6/ANXA6 抗体

Anti-Annexin-6/ANXA6 antibody

5

(4 Reviews)

|

(1 Publication)

Rabbit Polyclonal Annexin-6/ANXA6 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human, Mouse samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human ANXA6.

別名を表示する

ANX6, ANXA6, Annexin A6, 67 kDa calelectrin, Annexin VI, Annexin-6, Calphobindin-II, Chromobindin-20, Lipocortin VI, Protein III, p68, p70, CPB-II

5 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Annexin-6/ANXA6 antibody (AB196942)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Annexin-6/ANXA6 antibody (AB196942)

Immunohistochemical analysis of paraffin-embedded Human lung tissue labeling Annexin-6/ANXA6 with ab196942 at 1/200 dilution.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Annexin-6/ANXA6 antibody (AB196942)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Annexin-6/ANXA6 antibody (AB196942)

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling Annexin-6/ANXA6 with ab196942 at 1/200 dilution.

Immunocytochemistry/ Immunofluorescence - Anti-Annexin-6/ANXA6 antibody (AB196942)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-Annexin-6/ANXA6 antibody (AB196942)

Immunofluorescent analysis of A549 cells labeling Annexin-6/ANXA6 with ab196942 at 1/50 dilution.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Annexin-6/ANXA6 antibody (AB196942)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Annexin-6/ANXA6 antibody (AB196942)

Immunohistochemical analysis of paraffin-embedded Mouse liver tissue labeling Annexin-6/ANXA6 with ab196942 at 1/200 dilution.

Western blot - Anti-Annexin-6/ANXA6 antibody (AB196942)
  • WB

Supplier Data

Western blot - Anti-Annexin-6/ANXA6 antibody (AB196942)

All lanes:

Western blot - Anti-Annexin-6/ANXA6 antibody (ab196942) at 1/500 dilution

Lane 1:

K562 cell extract

Lane 2:

THP-1 cell extract

Lane 3:

MCF7 cell extract

Lane 4:

Mouse spleen extract

Lane 5:

Mouse heart extract

Lane 6:

Mouse liver extract

Lane 7:

Mouse skeletal muscle extract

Lane 8:

Mouse lung extract

Predicted band size: 76 kDa

false

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Mouse, Human

アプリケーション

IHC-P, WB, ICC/IF

applications

免疫原

Recombinant Fragment Protein within Human ANXA6. The exact immunogen used to generate this antibody is proprietary information.

P08133

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代替製品

Primary Antibodies

AB226410

Anti-Annexin-6/ANXA6 antibody

Western blot - Anti-Annexin-6/ANXA6 antibody (AB226410)

  • 0
  • 0
Primary Antibodies

AB31026

Anti-Annexin-6/ANXA6 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Annexin-6/ANXA6 antibody (AB31026)

  • 5
  • 5
Primary Antibodies

AB201023

Anti-Annexin-6/ANXA6 antibody [EPR19517]

RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Annexin-6/ANXA6 antibody [EPR19517] (AB201023)

  • 0
  • 0
Primary Antibodies

AB201024

Anti-Annexin-6/ANXA6 antibody [EPR19536]

RabMAb|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-Annexin-6/ANXA6 antibody [EPR19536] (AB201024)

  • 5
  • 1
Primary Antibodies

AB199422

Anti-Annexin-6/ANXA6 antibody [EPR17308] - N-terminal

RabMAb|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-Annexin-6/ANXA6 antibody [EPR17308] - N-terminal (AB199422)

  • 0
  • 0
Primary Antibodies

AB240359

Anti-Annexin-6/ANXA6 antibody [EPR19517] - BSA and Azide free

RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Annexin-6/ANXA6 antibody [EPR19517] - BSA and Azide free (AB240359)

  • 0
  • 0

組合せ製品

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AB267388

Anti-Thrombospondin 1 antibody [EPR22927-54]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant|Advanced Validation

Multiplex immunohistochemistry - Anti-Thrombospondin 1 antibody [EPR22927-54] (AB267388)

  • 2
  • 1
Primary Antibodies

AB255598

Anti-Granzyme B antibody [EPR22645-206]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Granzyme B antibody [EPR22645-206] (AB255598)

  • 4
  • 3
Primary Antibodies

AB75852

Anti-Cathepsin D antibody [EPR3057Y]

BOND RX™ Validated|RabMAb|Recombinant|20ul selling size

Western blot - Anti-Cathepsin D antibody [EPR3057Y] (AB75852)

  • 5
  • 11
Primary Antibodies

AB217345

Anti-CD63 antibody [EPR21151]

RabMAb|Recombinant|20ul selling size

Immunocytochemistry/ Immunofluorescence - Anti-CD63 antibody [EPR21151] (AB217345)

  • 4
  • 5
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
バッファー組成
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Annexin-6 also known as ANXA6 is a member of the annexin family of proteins. It has a mass of approximately 68 kDa and is expressed in various tissues with substantial presence in muscle and liver. This protein acts mechanically by binding to membranes in a calcium-dependent manner playing a role in membrane-associated processes such as endocytosis and exocytosis. Annexin-6 can also interact with cytoskeletal elements influencing cell structure and stability.
Biological function summary

Annexin-6 functions as a versatile scaffold that organizes multiprotein complexes. It modulates membrane trafficking processes and participates in signaling pathways within the cell. This protein can influence intracellular calcium homeostasis by interacting with calcium channels and transporters making it an integral part of cellular signaling and communication.

Pathways

Annexin-6 plays a role in the MAPK and PI3K/Akt signaling pathways. It associates with proteins such as Ras and Protein Kinase C impacting cell proliferation survival and differentiation. These interactions highlight the importance of annexin-6 in cellular responses to external stimuli and help regulate various physiological processes in the body.

Annexin-6 has been linked to cardiac disorders and cancer. In the context of cardiac health it interacts with proteins like phospholamban and calmodulin to influence heart muscle function and calcium regulation. In cancer annexin-6's involvement in the Akt signaling pathway can affect tumor growth and metastasis often interacting with other proteins like EGFR and HER2. This makes it a significant protein of interest in disease research and potential therapeutic targeting.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
See full target information ANXA6
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

FASEB journal : official publication of the Federa 29:3773-87 PubMed26023182

2015

Annexin A4 is a novel direct regulator of adenylyl cyclase type 5.

Applications

Unspecified application

Species

Unspecified reactive species

Alexander Heinick,Xenia Husser,Kirsten Himmler,Uwe Kirchhefer,Frank Nunes,Jan S Schulte,Matthias D Seidl,Christina Rolfes,John R Dedman,Marcia A Kaetzel,Volker Gerke,Wilhelm Schmitz,Frank U Müller
View all publications
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