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AB325667

Anti-ANK3 antibody [N106/36] - Chicken IgY (Chimeric)

Anti-ANK3 antibody [N106/36] - Chicken IgY (Chimeric)

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Chicken Monoclonal ANK-3 antibody. Suitable for IHC-P and reacts with Rat samples.

別名を表示する

Ankyrin-3, ANK-3, Ankyrin-G

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ANK3 antibody [N106/36] - Chicken IgY (Chimeric) (AB325667)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ANK3 antibody [N106/36] - Chicken IgY (Chimeric) (AB325667)

Representative section of formalin fixed, paraffin-embedded rat brain cerebral cortex showing neurons stained by ab325667 at 1 : 500 dilution (green). The stained sections were mounted with Fluoroshield with DAPI and DABCO mounting medium. DAPI nuclear stain (blue) shows cell nuclei. The antibody specifically stains the neuronal cell body and axon initial segment (AIS) in the cerebral cortex. Mag. 100X.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ANK3 antibody [N106/36] - Chicken IgY (Chimeric) (AB325667)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ANK3 antibody [N106/36] - Chicken IgY (Chimeric) (AB325667)

Representative section of formalin fixed, paraffin-embedded rat brain cerebral cortex showing neurons stained by ab325667 at 1 : 500 dilution (green). The stained sections were mounted with Fluoroshield with DAPI and DABCO mounting medium. DAPI nuclear stain (blue) shows cell nuclei. The antibody specifically stains the neuronal cell body and axon initial segment (AIS) in the cerebral cortex. Mag. 400X.

Key facts

宿主種

Chicken

クローン性

Monoclonal

クローン番号

N106/36

アイソタイプ

IgY

キャリアフリー

No

交差種

Rat

アプリケーション

IHC-P

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

特異性

Does not cross-react with Ankyrin-B.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rat": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/500", "IHCP-species-notes": "<p></p>" } } }

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification
精製に関する特記事項
This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of clone N106/36 with chicken IgY heavy and light constant regions. As such this antibody retains the same binding performance as the original clone N106/36 but can be detected using standard anti-chicken secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media.
バッファー組成
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
-20°C

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

ターゲットの情報

Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments (By similarity). In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Regulates KCNA1 channel activity in function of dietary Mg(2+) levels, and thereby contributes to the regulation of renal Mg(2+) reabsorption (By similarity). Required for intracellular adhesion and junctional conductance in myocytes, potentially via stabilization of GJA1/CX43 protein abundance and promotion of PKP2, GJA1/CX43, and SCN5A/Nav1.5 localization to cell-cell junctions (PubMed : 21617128).
See full target information Ank3

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