Anti-Angiopoietin 2/ANG2 抗体 (ab125692)
Key features and details
- Rabbit polyclonal to Angiopoietin 2/ANG2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Angiopoietin 2/ANG2 antibody
Angiopoietin 2/ANG2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Angiopoietin 2/ANG2 -
由来種
Rabbit -
特異性
At least three isoforms of ANGPT2 are known to exist; this antibody will detect all three isoforms. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human Angiopoietin 2/ANG2 (C terminal).
(Peptide available asab172727) -
ポジティブ･コントロール
- WB: Human Liver Tissue Lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab125692の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 56 kDa.
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| 特記事項 |
|---|
|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 56 kDa. |
ターゲット情報
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機能
Can induce tyrosine phosphorylation of TIE2. Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. -
配列類似性
Contains 1 fibrinogen C-terminal domain. -
ドメイン
The Fibrinogen C-terminal domain mediates interaction with the TEK/TIE2 receptor. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 285 Human
- Omim: 601922 Human
- SwissProt: O15123 Human
- Unigene: 583870 Human
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別名
- AGPT 2 antibody
- Agpt2 antibody
- ANG 2 antibody
see all
画像
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Western blot - Anti-Angiopoietin 2/ANG2 antibody (ab125692)Lane 1 : Anti-Angiopoietin 2/ANG2 antibody (ab125692) at 1 µg/ml
Lane 2 : Anti-Angiopoietin 2/ANG2 antibody (ab125692) at 2 µg/ml
All lanes : Human liver tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 56 kDa
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (2)
ab125692 は 2 報の論文で使用されています。
- Feng XF et al. Tetramethylpyrazine promotes stroke recovery by inducing the restoration of neurovascular unit and transformation of A1/A2 reactive astrocytes. Front Cell Neurosci 17:1125412 (2023). PubMed: 37051111
- Zhan Y et al. An MRI Study of Neurovascular Restorative After Combination Treatment With Xiaoshuan Enteric-Coated Capsule and Enriched Environment in Rats After Stroke. Front Neurosci 13:701 (2019). PubMed: 31354412
