Anti-Angiopoietin 1 抗体
Anti-Angiopoietin 1 antibody
4
(3 Reviews)
|
(64 Publications)
Rabbit Polyclonal Angiopoietin 1 antibody. Suitable for WB, IHC-P, ELISA, ICC/IF and reacts with Human, Mouse, Pig samples. Cited in 64 publications. Immunogen corresponding to Synthetic Peptide within Mouse Angpt1 aa 1-50.
別名を表示する
KIAA0003, ANGPT1, Angiopoietin-1, ANG-1
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Angiopoietin 1 antibody (AB8451)
ab8451 was diluted 1 : 500 to detect Angiopoietin 1 in human lung tissue. Tissue was formalin fixed and paraffin embedded. No pre-treatment of sample was required. The image shows the localization of antibody as the precipitated red signal, with a hematoxylin purple nuclear counter stain.
- WB
Supplier Data
Western blot - Anti-Angiopoietin 1 antibody (AB8451)
Supernatants of mouse-angiopoietin-expressing endothelial cells.
Lane 1 - wt endothelial cell
Lane 2 - mouse Ang-1 (clone 1-8) expressing cells
Lane 3 - mouse Ang-1 (clone 1-15) expressing cells
Lane 4 - mouse Ang-2 (clone 2-9) expressing cells
All lanes:
Western blot - Anti-Angiopoietin 1 antibody (ab8451)
Predicted band size: 57 kDa
false
This image is courtesy of Marion Scharpfenecker 2002
Reactivity data
製品の詳細
出荷温度及び保存条件
製品の状態
精製度
精製に関する特記事項
バッファー組成
出荷温度
短期保存温度
長期保存温度
分注に関する情報
保管に関する情報
補足情報
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Angiopoietin 1 supports the structural integrity of blood vessels by interacting with the Tie2 receptor as part of a signaling complex. It helps prevent vascular leak and promotes endothelial cell survival migration and adhesion. By playing such roles Angiopoietin 1 is fundamental for maintaining vascular homeostasis and facilitating proper blood flow throughout the body. It also influences the immune response by modulating endothelial functions.
Pathways
Angiopoietin 1's involvement is most notable within the PI3K/AKT pathway and the MAPK pathway which are important for signaling cell survival and growth. These pathways work closely with other proteins such as VEGF (Vascular Endothelial Growth Factor) in angiogenesis and vascular remodeling. Angiopoietin 1 interacts with its related pathways to ensure that blood vessels remain functional and adaptive to physiological changes.
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ターゲットの情報
文献 (64)
Recent publications for all applications. Explore the full list and refine your search
Scientific reports 15:20513 PubMed40593993
2025
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Cancer cell international 24:158 PubMed38711062
2024
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Biomedicines 11: PubMed37626761
2023
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Experimental biology and medicine (Maywood, N.J.) 248:732-745 PubMed37354086
2023
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Molecules (Basel, Switzerland) 28: PubMed37049657
2023
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PeerJ 11:e14562 PubMed36846460
2023
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Frontiers in molecular biosciences 9:1050112 PubMed36504711
2022
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Journal of cell communication and signaling 17:609-626 PubMed36326988
2022
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Frontiers in medicine 9:869284 PubMed35935760
2022
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Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 37:1844-1856 PubMed35451482
2022
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