Anti-AMH 抗体 [5/6] (ab24542)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AMH antibody [5/6] (ab24542)](https://www.abcam.co.jp/ps/products/24/ab24542/Images/ab24542-35262-anti-amh-antibody-5-6-immunohistochemistry.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AMH antibody [5/6] (ab24542)")
Key features and details
- Mouse monoclonal [5/6] to AMH
- Suitable for: IHC-P
- Reacts with: Mouse
- Isotype: IgG1
製品の概要
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製品名
Anti-AMH antibody [5/6]
AMH 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [5/6] to AMH -
由来種
Mouse -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Mouse
交差が予測される動物種: Rat, Cow, Pig
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免疫原
Synthetic peptide:
VPTAYAGKLLISLSEERISAHHVPNMVATEC
, corresponding to C terminal amino acids 527-557 of Human AMH. -
ポジティブ･コントロール
- Mouse ovary tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
Preservative: 0.09% Sodium azide
Constituent: Tissue culture supernatant -
Concentration information loading... -
精製度
Tissue culture supernatant -
ポリ/モノ
モノクローナル -
クローン名
5/6 -
ミエローマ
Sp2/0 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab24542の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
1/20 - 1/40. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 特記事項 |
|---|
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IHC-P
1/20 - 1/40. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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関連性
Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth. -
細胞内局在
Secreted -
参照データベース
- Entrez Gene: 280718 Cow
- Entrez Gene: 11705 Mouse
- Entrez Gene: 25378 Rat
- SwissProt: P27106 Mouse
- SwissProt: P49000 Rat
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別名
- Anti muellerian hormone antibody
- MIF antibody
- MIS antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AMH antibody [5/6] (ab24542)Ab24542, at a dilution of 1/20 to 1/40, staining formalin fixed paraffin embedded ovary tissue from a 25 day old mouse by Immunohystochemistry.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (12)
ab24542 は 12 報の論文で使用されています。
- Agopiantz M et al. Fertility in McCune Albright syndrome female: A case study focusing on AMH as a marker of ovarian dysfunction and a literature review. J Gynecol Obstet Hum Reprod 50:102171 (2021). PubMed: 34048958
- Pourjafari F et al. Evaluation of expression and serum concentration of anti-Mullerian hormone as a follicle growth marker following consumption of fennel and flaxseed extract in first-generation mice pups. BMC Complement Med Ther 21:90 (2021). PubMed: 33711998
- Maistrelli C et al. Precocious puberty in male wild boars: a possible explanation for the dramatic population increase in Germany and Europe. PeerJ 9:e11798 (2021). PubMed: 34322327
- Gao L et al. Therapeutic Effects of Modified Gengnianchun Formula on Stress-Induced Diminished Ovarian Reserve Based on Experimental Approaches and Network Pharmacology. Drug Des Devel Ther 14:4975-4992 (2020). PubMed: 33239863
- Hilbold E et al. Loss of Cx43 in Murine Sertoli Cells Leads to Altered Prepubertal Sertoli Cell Maturation and Impairment of the Mitosis-Meiosis Switch. Cells 9:N/A (2020). PubMed: 32164318