Anti-AMG 抗体 (ab153915)
Key features and details
- Rabbit polyclonal to AMG
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
-
製品名
Anti-AMG antibody -
製品の詳細
Rabbit polyclonal to AMG -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Monkey
-
免疫原
Recombinant fragment corresponding to Human AMG aa 1-191.
Database link: Q99217 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab153915の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 22 kDa.
|
|
| IHC-P | (2) |
Use at an assay dependent concentration. PubMed: 29089903
|
| 特記事項 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 22 kDa. |
|
IHC-P
Use at an assay dependent concentration. PubMed: 29089903 |
ターゲット情報
-
機能
Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel. -
関連疾患
Defects in AMELX are the cause of amelogenesis imperfecta hypoplastic type 1 (AIH1) [MIM:301200]. AIH1 is a X-linked defect of dental enamel formation. Teeth have only a thin layer of enamel with normal hardness. The thinness of the enamel makes the teeth appear small. -
配列類似性
Belongs to the amelogenin family. -
発生段階
Transiently but abundantly expressed by ameloblasts during tooth development. Amelogenin is the predominant protein in developing dental enamel. -
細胞内局在
Secreted > extracellular space > extracellular matrix. - Information by UniProt
-
参照データベース
- Entrez Gene: 265 Human
- Entrez Gene: 11704 Mouse
- Omim: 300391 Human
- SwissProt: Q99217 Human
- SwissProt: P63277 Mouse
- Unigene: 654436 Human
- Unigene: 391342 Mouse
-
別名
- AI1E antibody
- AIH1 antibody
- ALGN antibody
see all
画像
-
Western blot - Anti-AMG antibody (ab153915)Anti-AMG antibody (ab153915) at 1/500 dilution + NIH 3T3 whole cell lysate at 30 µg
Predicted band size: 22 kDa
12% SDS PAGE -
Western blot - Anti-AMG antibody (ab153915)Anti-AMG antibody (ab153915) at 1/500 dilution + Jurkat whole cell lysate at 30 µg
Predicted band size: 22 kDa
12% SDS PAGE
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (13)
ab153915 は 13 報の論文で使用されています。
- Said R et al. Deciphering the functions of Stromal Interaction Molecule-1 in amelogenesis using AmelX-iCre mice. Front Physiol 14:1100714 (2023). PubMed: 36935757
- Mitsiadis TA et al. Notch Signaling Pathway in Tooth Shape Variations throughout Evolution. Cells 12:N/A (2023). PubMed: 36899896
- Lee ES et al. The effects of 4-Phenylbutyric acid on ER stress during mouse tooth development. Front Physiol 13:1079355 (2022). PubMed: 36685173
- Bazina F et al. Partial epithelial-mesenchymal transition during enamel development. Clin Exp Dent Res 8:513-518 (2022). PubMed: 35182458
- Suzuki A et al. Crucial Roles of microRNA-16-5p and microRNA-27b-3p in Ameloblast Differentiation Through Regulation of Genes Associated With Amelogenesis Imperfecta. Front Genet 13:788259 (2022). PubMed: 35401675