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Anti-alpha 1d Adrenergic Receptor 抗体 (ab84402)

Submit a review Q&A (2)References (5)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-alpha 1d Adrenergic Receptor antibody (ab84402)
  • Western blot - Anti-alpha 1d Adrenergic Receptor antibody (ab84402)

Key features and details

  • Rabbit polyclonal to alpha 1d Adrenergic Receptor
  • Suitable for: WB, IHC-P
  • Reacts with: Human
  • Isotype: IgG

製品の概要

  • 製品名

    Anti-alpha 1d Adrenergic Receptor antibody
    alpha 1d Adrenergic Receptor 一次抗体 製品一覧

  • 製品の詳細

    Rabbit polyclonal to alpha 1d Adrenergic Receptor

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: WB, IHC-Pmore details

  • 種交差性

    交差種: Human
    交差が予測される動物種: Mouse, Rat, Drosophila melanogaster, Zebrafish

  • 免疫原

    Synthetic peptide corresponding to Human alpha 1d Adrenergic Receptor (internal sequence). A 12 amino acid peptide from the internal residues of human alpha 1d Adrenergic Receptor.
    Database link: P25100

  • ポジティブ･コントロール

    • WB: A549 and MCF7 cell lysates. IHC-P: Human cervical cancer tissue.

  • 特記事項

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab84402の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
WB
1/500 - 1/2000. Predicted molecular weight: 60 kDa.
IHC-P
1/50 - 1/200.
特記事項
WB
1/500 - 1/2000. Predicted molecular weight: 60 kDa.
IHC-P
1/50 - 1/200.

ターゲット情報

  • 機能

    This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

  • 配列類似性

    Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1D sub-subfamily.

  • 細胞内局在

    Cell membrane.
  • Information by UniProt

  • 参照データベース

    see all

  • 別名

    • ADA1D_HUMAN antibody
    • Adra1 antibody
    • Adra1a antibody
    • Adra1d antibody
    • ADRA1R antibody
    • Adrd1 antibody
    • Adrenergic alpha1A receptor antibody
    • Adrenergic alpha1D receptor antibody
    • Adrenergic receptor alpha 1d antibody
    • Adrenergic receptor delta1 antibody
    • Adrenoceptor alpha 1D antibody
    • Alpha 1D adrenoceptor antibody
    • Alpha 1D adrenoreceptor antibody
    • Alpha adrenergic receptor 1a antibody
    • Alpha-1A adrenergic receptor antibody
    • Alpha-1D adrenergic receptor antibody
    • Alpha-1D adrenoceptor antibody
    • Alpha-1D adrenoreceptor antibody
    • Alpha-adrenergic receptor 1a antibody
    • ALPHA1 antibody
    • Alpha1A adrenergic receptor antibody
    • Alpha1D adrenergic receptor antibody
    • Alpha1DAR antibody
    • DAR antibody
    • dJ779E11.2 antibody
    • Gpcr8 antibody
    • RA42 antibody
    • Spr8 antibody
    see all

画像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-alpha 1d Adrenergic Receptor antibody (ab84402)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-alpha 1d Adrenergic Receptor antibody (ab84402)

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human cervical cancer tissue labelling alpha 1d Adrenergic Receptor with ab84402 at a dilution of 1/100.

  • Western blot - Anti-alpha 1d Adrenergic Receptor antibody (ab84402)
    Western blot - Anti-alpha 1d Adrenergic Receptor antibody (ab84402)
    All lanes : Anti-alpha 1d Adrenergic Receptor antibody (ab84402) at 1/1000 dilution

    Lane 1 : A549 lysate
    Lane 2 : MCF7 lysate

    Predicted band size: 60 kDa
    Observed band size: 60 kDa

参考文献 (5)

ab84402 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab84402 は 5 報の論文で使用されています。

  • Enten GA  et al. α1B/D-adrenoceptors regulate chemokine receptor-mediated leukocyte migration via formation of heteromeric receptor complexes. Proc Natl Acad Sci U S A 119:e2123511119 (2022). PubMed: 35537053
  • Lee JY  et al. Expression of bladder a1-adrenoceptor subtype after relief of partial bladder outlet obstruction in a rat model. Investig Clin Urol 61:297-303 (2020). PubMed: 32377606
  • Tang JM  et al. Response Gene to Complement 32 Maintains Blood Pressure Homeostasis by Regulating a-Adrenergic Receptor Expression. Circ Res 123:1080-1090 (2018). PubMed: 30355157
  • Tripathi A  et al. Heteromerization of chemokine (C-X-C motif) receptor 4 with a1A/B-adrenergic receptors controls a1-adrenergic receptor function. Proc Natl Acad Sci U S A 112:E1659-68 (2015). PubMed: 25775528
  • Juncos R  et al. Selective enhancement of contractions to a1-adrenergic receptor activation in the aorta of mice with sickle cell disease. J Cardiovasc Pharmacol 57:263-6 (2011). PubMed: 21107280

レビューと Q&A

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レビューを送る 質問を送る

1-2 of 2 Abreviews or Q&A

Question

A customer would like to know the concentration of this antibody, lot #: GR68210

Can you please advise?

Thank you for your help J

Kind regards,

Read More
Answer

Thank you for contacting us.

The concentration of this lot is 0.5mg/ml.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Read More

Question

Greetings- I would like to kindly ask you for sending me the list of replacements for the following antibodies: ab3546, ab12923 and ab12935. Thank you in advance for help.

Read More
Answer

Thank you very much for your interest in our adrenergic Receptor antibodies. These are the alternatives we could recommend: Anti-beta 1 Adrenergic Receptor antibody (replacement for ab3546): The rabbit polyclonal ab3442 which is guaranteed to work with a number of species including mouse and rat in Western blot and Immunocytochemistry/Immunofluorescence (ICC/IF). To our knowledge, ab3442 has not been tested in Immunhistochemistry on frozen sections (IHC-Fr). Therefore, I can offer a discount off a future purchase if you buy it now, test it in IHC-Fr and submit feedback to us in the form of an Abreview. It doesn’t matter whether the Abreview is positive or negative, we would just really like to receive your feedback. The discount would be to the value of 1 free primary antibody. Please contact us again for more detailed information if you are interested. Click here (or use the following: https://www.abcam.com/beta-1-Adrenergic-Receptor-antibody-ab3442.html). Anti-alpha 1d Adrenergic Receptor antibody (replacement for ab12923): The rabbit polyclonal ab84402 which is guaranteed to work with a number of species including human in Western blot and ELISA. This antibody has not been tested in Immunhistochemistry on paraffin-embedded sections (IHC-P). Again, if you would like to test this, you are eligible for our testing discount program if the antibody has not yet been purchased. Click here (or use the following: https://www.abcam.com/alpha-1d-Adrenergic-Receptor-antibody-ab84402.html). Anti-alpha 1c Adrenergic Receptor antibody (replacement for ab12935): The rabbit polyclonal ab96783 or the mouse monoclonal ab87990 which are guaranteed to work with a number of species including human in Western blot and ELISA. These antibodies have not been tested in Immunhistochemistry on paraffin-embedded sections (IHC-P) and here you are eligible for our testing discount program. Click here (or use the following: https://www.abcam.com/alpha-1a-Adrenergic-ReceptorADRA1A-antibody-ab96783.html). Click here (or use the following: https://www.abcam.com/alpha-1a-Adrenergic-ReceptorADRA1A-antibody-ab87990.html). The terms and conditions applicable to these offers can be found here: www.abcam.com/collaborationdiscount. I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

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