Anti-alpha 1 Fetoprotein 抗体 (ab87635)
Key features and details
- Rabbit polyclonal to alpha 1 Fetoprotein
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
-
製品名
Anti-alpha 1 Fetoprotein antibody
alpha 1 Fetoprotein 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to alpha 1 Fetoprotein -
由来種
Rabbit -
特異性
ab87635 does not cross react to human lactoferrin, bovine lactoferrin or bovine serum albumin. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Full length native protein (purified) corresponding to Human alpha 1 Fetoprotein. Purified human alpha 1 Fetoprotein.
-
ポジティブ･コントロール
- alpha 1 fetoprotein
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
ab87635 was affinity-purified and isolated on immobilized antigen-affinity column and supplied as stabilized product. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Conjugation kits
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab87635の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500. Predicted molecular weight: 69 kDa.
|
| 特記事項 |
|---|
|
WB
1/500. Predicted molecular weight: 69 kDa. |
ターゲット情報
-
機能
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. -
組織特異性
Plasma. Synthesized by the fetal liver and yolk sac. -
配列類似性
Belongs to the ALB/AFP/VDB family.
Contains 3 albumin domains. -
発生段階
Occurs in the plasma of fetuses more than 4 weeks old, reaches the highest levels during the 12th-16th week of gestation, and drops to trace amounts after birth. The serum level in adults is usually less than 40 ng/ml. AFP occurs also at high levels in the plasma and ascitic fluid of adults with hepatoma. -
翻訳後修飾
Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence.
Sulfated. -
細胞内局在
Secreted. - Information by UniProt
-
参照データベース
- Entrez Gene: 174 Human
- Omim: 104150 Human
- SwissProt: P02771 Human
- Unigene: 518808 Human
-
別名
- Afp antibody
- AFPD antibody
- Alpha fetoglobulin antibody
see all
画像
-
Western blot - Anti-alpha 1 Fetoprotein antibody (ab87635)All lanes : Anti-alpha 1 Fetoprotein antibody (ab87635) at 1/500 dilution
Lane 1 : Human alpha Fetoprotein
Lane 2 : Human Lactoferrin
Lane 3 : Human serum albumin
Predicted band size: 69 kDa
Observed band size: 69 kDa
Additional bands at: 57 kDa (possible degradation product)
データシートおよび資料
-
Datasheet download
参考文献 (1)
ab87635 は 1 報の論文で使用されています。
- Quattrocelli M et al. Equine-Induced Pluripotent Stem Cells Retain Lineage Commitment Toward Myogenic and Chondrogenic Fates. Stem Cell Reports 6:55-63 (2016). PubMed: 26771353
