Alexa Fluor® 647 Anti-M6PR (cation independent) 抗体 [MEM-238] (ab187589)
![Flow Cytometry - Alexa Fluor® 647 Anti-M6PR (cation independent) antibody [MEM-238] (ab187589)](https://www.abcam.co.jp/ps/products/187/ab187589/Images/ab187589-1-anti-mcpr-calcium-independent-antibody-mem238-flow-cytometry-peripheral-blood-human.jpg "Flow Cytometry - Alexa Fluor® 647 Anti-M6PR (cation independent) antibody [MEM-238] (ab187589)")
Key features and details
- Alexa Fluor® 647 Mouse monoclonal [MEM-238] to M6PR (cation independent)
- Suitable for: Flow Cyt, Flow Cyt (Intra)
- Reacts with: Human
- Conjugation: Alexa Fluor® 647. Ex: 652nm, Em: 668nm
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
Alexa Fluor® 647 Anti-M6PR (cation independent) antibody [MEM-238]
M6PR (cation independent) 一次抗体 製品一覧 -
製品の詳細
Alexa Fluor® 647 Mouse monoclonal [MEM-238] to M6PR (cation independent) -
由来種
Mouse -
標識
Alexa Fluor® 647. Ex: 652nm, Em: 668nm -
アプリケーション
適用あり: Flow Cyt, Flow Cyt (Intra)more details -
種交差性
交差種: Human
交差が予測される動物種: Non human primates
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免疫原
Tissue, cells or virus corresponding to Human M6PR (cation independent). Recombinant Vaccinia virus encoding M6PR (cation independent) .
Database link: P11717 -
ポジティブ･コントロール
- Flow Cyt: Human blood cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Store In the Dark. -
バッファー
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: 99% PBS, 0.2% BSA -
Concentration information loading... -
精製度
Size exclusion -
ポリ/モノ
モノクローナル -
クローン名
MEM-238 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab187589の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use 4µl for 106 cells.
4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. |
|
| Flow Cyt (Intra) |
Use 4µl for 106 cells.
4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. |
| 特記事項 |
|---|
|
Flow Cyt
Use 4µl for 106 cells. 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. |
|
Flow Cyt (Intra)
Use 4µl for 106 cells. 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. |
ターゲット情報
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機能
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. -
配列類似性
Belongs to the MRL1/IGF2R family.
Contains 1 fibronectin type-II domain. -
ドメイン
Contains 15 repeating units of approximately 147 AA harboring four disulfide bonds each. The most highly conserved region within the repeat consists of a stretch of 13 AA that contains cysteines at both ends. -
細胞内局在
Lysosome membrane. Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface. - Information by UniProt
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参照データベース
- Entrez Gene: 3482 Human
- Omim: 147280 Human
- SwissProt: P11717 Human
- Unigene: 487062 Human
- Unigene: 673278 Human
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別名
- 300 kDa mannose 6 phosphate receptor antibody
- 300 kDa mannose 6-phosphate receptor antibody
- Cation independent mannose 6 phosphate receptor antibody
see all
画像
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Flow Cytometry - Alexa Fluor® 647 Anti-M6PR (cation independent) antibody [MEM-238] (ab187589)Flow cytometry analysis of human peripheral blood labeling MCPR (calcium independent) /CD222 using ab187589 at 4 µL/100 µL whole blood. Surface staining.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab187589 は論文での使用が確認できていません。
