JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB312669

Alexa Fluor® 568 Anti-PHYHD1 抗体 [EPR13313(B)]

Alexa Fluor® 568 Anti-PHYHD1 antibody [EPR13313(B)]

Be the first to review this product! Submit a review

|

(0 Publication)

Rabbit Recombinant Monoclonal PHYHD1 antibody - conjugated to Alexa Fluor® 568.

別名を表示する

Phytanoyl-CoA dioxygenase domain-containing protein 1, Protein PHYHD1, PHYHD1

関連する標識済み抗体及び組成の異なる製品 (8)

  • Unconjugated

    Anti-PHYHD1 antibody [EPR13313(B)]

  • 660 APC

    APC Anti-PHYHD1 antibody [EPR13313(B)]

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-PHYHD1 antibody [EPR13313(B)]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-PHYHD1 antibody [EPR13313(B)]

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-PHYHD1 antibody [EPR13313(B)]

  • 578 PE

    PE Anti-PHYHD1 antibody [EPR13313(B)]

  • 617 Alexa Fluor® 594

    Alexa Fluor® 594 Anti-PHYHD1 antibody [EPR13313(B)]

  • Carrier free

    Anti-PHYHD1 antibody [EPR13313(B)] - BSA and Azide free

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR13313(B)

アイソタイプ

IgG

標識

Alexa Fluor® 568

励起波長/蛍光波長

Ex: 578nm, Em: 603nm

キャリアフリー

No

アプリケーション

Antibody Labelling, Target Binding Affinity

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

style
left-column
style
left-column

製品の詳細

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

style
left-column

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: 68% PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle|Store in the dark
style
left-column

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

The PHYHD1 protein also known as Phytanoyl-CoA Dioxygenase Domain Containing 1 functions as an enzyme involved in metabolic processes. It carries out oxidation reactions specifically hydroxylation on specific substrate molecules. PHYHD1 has a molecular mass of approximately 44 kDa making it a moderate-sized protein. Expressed in various tissues including the liver and kidneys PHYHD1 plays a significant role in managing metabolic activity within these regions contributing to cellular homeostasis and overall metabolic health.
Biological function summary

PHYHD1 participates in cellular metabolism by catalyzing reactions that modify fatty acids. This protein is involved in the breakdown of phytanic acid a complex fatty acid. In these reactions PHYHD1 may function independently or as part of larger protein complexes facilitating intricate steps that convert fatty acids into more usable forms. This process represents a significant part of lipid metabolism illustrating PHYHD1's role in maintaining the balance of lipid levels and energy within the cell.

Pathways

Researchers identified PHYHD1 in pathways related to fatty acid metabolism and chain elongation. In the context of the peroxisomal alpha-oxidation pathway PHYHD1 interacts with important proteins such as Peroxin and Phytanoyl-CoA alpha-hydroxylase which together assist in processing certain fatty acids. Additionally PHYHD1 links to other metabolic pathways involving oxidation reactions highlighting its central role in modulating lipid and energy metabolism.

Studies associate PHYHD1 with conditions such as Refsum Disease and disorders of fatty acid metabolism. Refsum Disease a genetic disorder involving the accumulation of phytanic acid sees a loss or reduction in PHYHD1 activity leading to severe symptoms. Through these associations PHYHD1 interacts with proteins like the phytanoyl-CoA hydroxylase enzyme exemplifying its critical role in the breakdown of fatty acids and linking its activity directly to disease state development and progression.
style
left-column
style
left-column

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

ターゲットの情報

2-oxoglutarate(2OG)-dependent dioxygenase that catalyzes the conversion of 2-oxoglutarate to succinate and CO(2) in an iron-dependent manner (PubMed : 21530488). However, does not couple 2OG turnover to the hydroxylation of acyl-coenzyme A derivatives, implying that it is not directly involved in phytanoyl coenzyme-A metabolism (PubMed : 21530488). Does not show detectable activity towards fatty acid CoA thioesters (PubMed : 21530488).. Isoform 2. Isoform 2 probably lacks enzyme activity.. Isoform 3. Isoform 3 probably lacks enzyme activity.
See full target information PHYHD1
style
left-column
style
left-column

Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
保証に関する詳細については利用規約をご確認ください。
style
left-column
style
right-column

関連製品

Select an associated product type
Alternative Version
Primary Antibodies

AB250730

Anti-PHYHD1 antibody [EPR13313(B)] - BSA and Azide free

primary-antibodies

phyhd1-antibody-epr13313b-bsa-and-azide-free-ab250730

0

(0 reviews)

style
bg-slate-100

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com