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AB312491

Alexa Fluor® 568 Anti-Extracellular matrix protein 1 抗体 [EPR6701]

Alexa Fluor® 568 Anti-Extracellular matrix protein 1 antibody [EPR6701]

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Rabbit Recombinant Monoclonal Extracellular matrix protein 1 antibody - conjugated to Alexa Fluor® 568.

別名を表示する

Extracellular matrix protein 1, Secretory component p85, ECM1

関連する標識済み抗体及び組成の異なる製品 (10)

  • Unconjugated

    Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • 578 PE

    PE Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • 660 APC

    APC Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • 617 Alexa Fluor® 594

    Alexa Fluor® 594 Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • HRP

    HRP Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • 775 Alexa Fluor® 750

    Alexa Fluor® 750 Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • Carrier free

    Anti-Extracellular matrix protein 1 antibody [EPR6701] - BSA and Azide free

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR6701

アイソタイプ

IgG

標識

Alexa Fluor® 568

励起波長/蛍光波長

Ex: 578nm, Em: 603nm

キャリアフリー

No

アプリケーション

Target Binding Affinity, Antibody Labelling

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

特異性

The rat recommendation is based on the WB results. We do not guarantee IHC-P for rat.

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下記製品にもご興味をお持ちいただけるかもしれません:

AB246524

Human ECM1 ELISA Kit

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1 Reviews

製品ページを見る
こちらの製品も推奨する理由

この製品は、同様の実験や関連する研究で広く使用されていることから推奨させていただいております。

お客様の実験に適するかご確認いただくため、必ず製品データシートをご確認いただくことをお勧めいたします。ご不明点等ございましたら、テクニカルサポートチームまでお問い合わせください。

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製品の詳細

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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: 68% PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle|Store in the dark
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Extracellular matrix protein 1 often called ECM1 is a matrix protein involved in various mechanical functions in the body. This protein weighs approximately 61 kDa and is widely expressed in human tissues including skin bone lung and brain. ECM1 also goes by the name H3300 vector used in some experimental contexts. Being an extracellular matrix (ECM) component ECM1 plays roles in tissue organization influencing matrix proteins' structural integrity.
Biological function summary

ECM1 contributes to cell-matrix interactions and regulates various cell behaviors such as adhesion proliferation and differentiation. It does this by binding to other ECM proteins and is known not to be part of a specific complex. ECM1 facilitates communication between the cellular environment and matrix thereby supporting the architecture and dynamics of tissues. It modulates angiogenesis linking it with processes like wound healing and vascular development.

Pathways

ECM1 functions within the context of key signaling routes such as the PI3K/AKT pathway known for roles in cell growth and survival. ECM1 interacts with other proteins including matrix metalloproteinases contributing to matrix remodeling activities important for cellular migration and invasion. Cumulatively these interactions highlight ECM1’s place in connective tissue organization and regenerative processes.

ECM1’s dysregulation links it with lipoid proteinosis and skin conditions like Atopic Dermatitis. Imbalances in ECM1 expression or function can lead to abnormal ECM assembly influencing these diseases' development. Moreover abnormalities in ECM1 can alter the behavior of related proteins such as collagen impacting skin integrity and permeability. Understanding ECM1’s role could provide insights into therapeutic strategies for these conditions.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity.
See full target information Extracellular matrix protein 1
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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
保証に関する詳細については利用規約をご確認ください。
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関連製品

Select an associated product type
Alternative Version
Primary Antibodies

AB242391

Anti-Extracellular matrix protein 1 antibody [EPR6701] - BSA and Azide free

primary-antibodies

extracellular-matrix-protein-1-antibody-epr6701-bsa-and-azide-free-ab242391

0

(0 reviews)

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