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AB312569

Alexa Fluor® 568 Anti-Estrogen Inducible Protein pS2 抗体 [EPR3972]

Alexa Fluor® 568 Anti-Estrogen Inducible Protein pS2 antibody [EPR3972]

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Rabbit Recombinant Monoclonal Estrogen Inducible Protein pS2 antibody - conjugated to Alexa Fluor® 568.

別名を表示する

BCEI, PS2, TFF1, Trefoil factor 1, Breast cancer estrogen-inducible protein, PNR-2, Polypeptide P1.A, Protein pS2, hP1.A

関連する標識済み抗体及び組成の異なる製品 (10)

  • Unconjugated

    Anti-Estrogen Inducible Protein pS2 antibody [EPR3972]

  • 578 PE

    PE Anti-Estrogen Inducible Protein pS2 antibody [EPR3972]

  • 660 APC

    APC Anti-Estrogen Inducible Protein pS2 antibody [EPR3972]

  • 617 Alexa Fluor® 594

    Alexa Fluor® 594 Anti-Estrogen Inducible Protein pS2 antibody [EPR3972]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-Estrogen Inducible Protein pS2 antibody [EPR3972]

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-Estrogen Inducible Protein pS2 antibody [EPR3972]

  • HRP

    HRP Anti-Estrogen Inducible Protein pS2 antibody [EPR3972]

  • 775 Alexa Fluor® 750

    Alexa Fluor® 750 Anti-Estrogen Inducible Protein pS2 antibody [EPR3972]

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-Estrogen Inducible Protein pS2 antibody [EPR3972]

  • Carrier free

    Anti-Estrogen Inducible Protein pS2 antibody [EPR3972] - BSA and Azide free

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR3972

アイソタイプ

IgG

標識

Alexa Fluor® 568

励起波長/蛍光波長

Ex: 578nm, Em: 603nm

キャリアフリー

No

アプリケーション

Antibody Labelling, Target Binding Affinity

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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こちらの製品も推奨する理由

この製品は、同様の実験や関連する研究で広く使用されていることから推奨させていただいております。

お客様の実験に適するかご確認いただくため、必ず製品データシートをご確認いただくことをお勧めいたします。ご不明点等ございましたら、テクニカルサポートチームまでお問い合わせください。

製品の詳細

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: 68% PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle|Store in the dark

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

The Estrogen Inducible Protein pS2 also known as Trefoil Factor 1 (TFF1) is a small protein with a mass of about 6.6 kDa. It is mainly expressed in the mucosa of the stomach and other tissues responsive to estrogen. pS2 functions mechanically as part of the trefoil factor family known for its role in mucosal protection and repair. pS2 has a distinctive three-loop structure which is key to its interaction with other molecules and substrates in the cellular environment.
Biological function summary

This trefoil factor plays a significant role in the process of epithelial regeneration and maintaining gastrointestinal tract integrity. It is not known to be part of a complex but works through interaction with various growth factors and cytokines. Its expression is regulated by estrogen making pS2 significant in estrogen-responsive tissues. These interactions contribute to maintaining the stability of epithelial lining aiding in cellular migration and wound healing.

Pathways

PS2 influences cellular signaling involved in the gastric mucosal defense mainly interacting with the Epidermal Growth Factor (EGF) pathway. It modulates the pathway's effects on cell proliferation and migration. Its role is linked to the mitigation of tissue damage indicating a connection with other proteins like the EGF receptor contributing to the repair and defense mechanisms of epithelial tissues.

PS2 has gained attention in breast cancer research. Its expression correlates with hormone receptor-positive breast cancer making it a potential biomarker for the disease. Additionally aberrant expression levels of pS2 might relate to gastric cancer where it plays a role in tumor progression and response to therapy. pS2 is closely connected to estrogen receptor proteins which guide its involvement in these cancers influencing prognosis and treatment strategies.

製品プロトコール

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ターゲットの情報

Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.
See full target information TFF1

Abcam product promise

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保証に関する詳細については利用規約をご確認ください。

関連製品

Select an associated product type
Alternative Version
Primary Antibodies

AB239908

Anti-Estrogen Inducible Protein pS2 antibody [EPR3972] - BSA and Azide free

primary-antibodies

estrogen-inducible-protein-ps2-antibody-epr3972-bsa-and-azide-free-ab239908

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(0 reviews)

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