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AB312538

Alexa Fluor® 568 Anti-CTBP2 抗体 [EPR7611(B)]

Alexa Fluor® 568 Anti-CTBP2 antibody [EPR7611(B)]

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Rabbit Recombinant Monoclonal CTBP2 antibody - conjugated to Alexa Fluor® 568.

別名を表示する

C-terminal-binding protein 2, CtBP2, CTBP2

関連する標識済み抗体及び組成の異なる製品 (10)

  • Unconjugated

    Anti-CTBP2 antibody [EPR7611(B)]

  • 660 APC

    APC Anti-CTBP2 antibody [EPR7611(B)]

  • HRP

    HRP Anti-CTBP2 antibody [EPR7611(B)]

  • 578 PE

    PE Anti-CTBP2 antibody [EPR7611(B)]

  • 617 Alexa Fluor® 594

    Alexa Fluor® 594 Anti-CTBP2 antibody [EPR7611(B)]

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-CTBP2 antibody [EPR7611(B)]

  • 775 Alexa Fluor® 750

    Alexa Fluor® 750 Anti-CTBP2 antibody [EPR7611(B)]

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-CTBP2 antibody [EPR7611(B)]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-CTBP2 antibody [EPR7611(B)]

  • Carrier free

    Anti-CTBP2 antibody [EPR7611(B)] - BSA and Azide free

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR7611(B)

アイソタイプ

IgG

標識

Alexa Fluor® 568

励起波長/蛍光波長

Ex: 578nm, Em: 603nm

キャリアフリー

No

アプリケーション

Antibody Labelling, Target Binding Affinity

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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製品の詳細

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: 68% PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle|Store in the dark
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

CTBP2 also known as C-terminal binding protein 2 is a transcriptional co-repressor involved in regulating gene expression. It is a protein with a molecular mass of approximately 48 kDa. CTBP2 is expressed in various tissues with high levels in neural muscular and epithelial cells. Mechanically CTBP2 operates by interacting with transcription factors and histone-modifying enzymes modulating chromatin structure to control access to DNA.
Biological function summary

CTBP2 plays a significant role in cellular processes such as development and differentiation. It frequently acts as part of multi-protein complexes interacting with diverse partners to facilitate transcriptional repression. These interactions are essential for balancing gene activity ensuring appropriate tissue development and function. CTBP2 influences cellular dynamics by regulating target genes implicated in growth survival and metabolic pathways.

Pathways

CTBP2 integrates into significant signaling pathways like Wnt and TGF-beta where it reinforces regulatory control by interacting with critical factors such as beta-catenin or Smad proteins. It collaborates with other proteins like CTBP1 dictating cellular responses and influencing pathophysiological processes. By coordinating these pathways CTBP2 supports cellular homeostasis impacting tissues in response to external and internal cues.

CTBP2 has associations with cancer and neurodegenerative diseases. Its overexpression or altered activity links to cancer progression as it promotes a transcriptional environment conducive to tumor growth. Proteins such as E-cadherin connect with CTBP2 in metastasis exemplifying its role in cancer cell dissemination. Additionally changes in CTBP2 function relate to neurodegenerative conditions affecting nerve cell survival and synaptic activity pointing to its involvement in neuronal health and disease mechanisms.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity).. Isoform 2 probably acts as a scaffold for specialized synapses.
See full target information CTBP2
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Abcam product promise

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保証に関する詳細については利用規約をご確認ください。
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関連製品

Select an associated product type
Alternative Version
Primary Antibodies

AB248197

Anti-CTBP2 antibody [EPR7611(B)] - BSA and Azide free

primary-antibodies

ctbp2-antibody-epr7611b-bsa-and-azide-free-ab248197

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