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AB312381

Alexa Fluor® 568 Anti-CD3 zeta (phospho Y142) 抗体 [EP265(2)Y]

Alexa Fluor® 568 Anti-CD3 zeta (phospho Y142) antibody [EP265(2)Y]

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Rabbit Recombinant Monoclonal CD3 zeta phospho Y142 antibody - conjugated to Alexa Fluor® 568.

別名を表示する

CD247, CD3Z, T3Z, TCRZ, T-cell surface glycoprotein CD3 zeta chain, T-cell receptor T3 zeta chain

関連する標識済み抗体及び組成の異なる製品 (8)

  • Unconjugated

    Anti-CD3 zeta (phospho Y142) antibody [EP265(2)Y]

  • 660 APC

    APC Anti-CD3 zeta (phospho Y142) antibody [EP265(2)Y]

  • 617 Alexa Fluor® 594

    Alexa Fluor® 594 Anti-CD3 zeta (phospho Y142) antibody [EP265(2)Y]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-CD3 zeta (phospho Y142) antibody [EP265(2)Y]

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-CD3 zeta (phospho Y142) antibody [EP265(2)Y]

  • 578 PE

    PE Anti-CD3 zeta (phospho Y142) antibody [EP265(2)Y]

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-CD3 zeta (phospho Y142) antibody [EP265(2)Y]

  • Carrier free

    Anti-CD3 zeta (phospho Y142) antibody [EP265(2)Y] - BSA and Azide free

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EP265(2)Y

アイソタイプ

IgG

標識

Alexa Fluor® 568

励起波長/蛍光波長

Ex: 578nm, Em: 603nm

キャリアフリー

No

アプリケーション

Antibody Labelling, Target Binding Affinity

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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製品の詳細

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: 68% PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle|Store in the dark
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways (PubMed : 1384049, PubMed : 1385158, PubMed : 2470098, PubMed : 7509083). CD3Z ITAMs phosphorylation creates multiple docking sites for the protein kinase ZAP70 leading to ZAP70 phosphorylation and its conversion into a catalytically active enzyme (PubMed : 7509083). Plays an important role in intrathymic T-cell differentiation. Additionally, participates in the activity-dependent synapse formation of retinal ganglion cells (RGCs) in both the retina and dorsal lateral geniculate nucleus (dLGN) (By similarity).
See full target information CD247 phospho Y142
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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
保証に関する詳細については利用規約をご確認ください。
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関連製品

Select an associated product type
Alternative Version
Primary Antibodies

AB245765

Anti-CD3 zeta (phospho Y142) antibody [EP265(2)Y] - BSA and Azide free

primary-antibodies

cd3-zeta-phospho-y142-antibody-ep2652y-bsa-and-azide-free-ab245765

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