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リコンビナントRabMAb

Alexa Fluor® 555 Anti-PSD95 抗体 [EPR23124-118] - Synaptic Marker (ab302571)

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Immunohistochemistry (Frozen sections) - Alexa Fluor® 555 Anti-PSD95 antibody [EPR23124-118] - Synaptic Marker (ab302571)
  • Immunohistochemistry (Frozen sections) - Alexa Fluor® 555 Anti-PSD95 antibody [EPR23124-118] - Synaptic Marker (ab302571)
  • Alexa Fluor® 555 Anti-PSD95 antibody [EPR23124-118] - Synaptic Marker (ab302571)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Alexa Fluor® 555 Rabbit monoclonal [EPR23124-118] to PSD95 - Synaptic Marker
  • Suitable for: IHC-Fr
  • Reacts with: Mouse, Rat
  • Conjugation: Alexa Fluor® 555. Ex: 555nm, Em: 565nm

Conjugates logo Related conjugates and formulations

Carrier Free Unconjugated Unconjugated

製品の概要

  • 製品名

    Alexa Fluor® 555 Anti-PSD95 antibody [EPR23124-118] - Synaptic Marker
    PSD95 一次抗体 製品一覧

  • 製品の詳細

    Alexa Fluor® 555 Rabbit monoclonal [EPR23124-118] to PSD95 - Synaptic Marker

  • 由来種

    Rabbit

  • 標識

    Alexa Fluor® 555. Ex: 555nm, Em: 565nm

  • アプリケーション

    適用あり: IHC-Frmore details

  • 種交差性

    交差種: Mouse, Rat

  • 免疫原

    Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.

  • ポジティブ･コントロール

    • IHC-Fr: Mouse and rat cerebellum, fresh frozen tissue sections.

  • 特記事項

    This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com.

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

    Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company. The Alexa Fluor® dye included in this product is provided under an intellectual property license from Life Technologies Corporation. As this product contains the Alexa Fluor® dye, the purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). As this product contains the Alexa Fluor® dye the sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: in manufacturing; (ii) to provide a service, information, or data in return for payment (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are sold for use in research. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab302571の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
IHC-Fr
1/50.
特記事項
IHC-Fr
1/50.

ターゲット情報

  • 機能

    Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.

  • 組織特異性

    Brain.

  • 配列類似性

    Belongs to the MAGUK family.
    Contains 1 guanylate kinase-like domain.
    Contains 3 PDZ (DHR) domains.
    Contains 1 SH3 domain.

  • ドメイン

    The PDZ domain 3 mediates interaction with ADR1B.
    The L27 domain near the N-terminus of isoform 2 is required for HGS/HRS-dependent targeting to postsynaptic density.

  • 翻訳後修飾

    Palmitoylation of isoform 1 is required for targeting to postsynaptic density.

  • 細胞内局在

    Cell membrane. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, axon. Cell junction, synapse. High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of Purkinje cells.
  • Information by UniProt

  • 参照データベース

    • 別名

      • Discs large homolog 4 antibody
      • Disks large homolog 4 antibody
      • DLG 4 antibody
      • Dlg4 antibody
      • DLG4_HUMAN antibody
      • FLJ97752 antibody
      • FLJ98574 antibody
      • Human post synaptic density protein 95 antibody
      • Post synaptic density protein 95 antibody
      • Postsynaptic density protein 95 antibody
      • PSD 95 antibody
      • PSD-95 antibody
      • PSD95 antibody
      • SAP 90 antibody
      • SAP-90 antibody
      • SAP90 antibody
      • Synapse associated protein 90 antibody
      • Synapse-associated protein 90 antibody
      • Tax interaction protein 15 antibody
      see all

    画像

    • Immunohistochemistry (Frozen sections) - Alexa Fluor® 555 Anti-PSD95 antibody [EPR23124-118] - Synaptic Marker (ab302571)
      Immunohistochemistry (Frozen sections) - Alexa Fluor® 555 Anti-PSD95 antibody [EPR23124-118] - Synaptic Marker (ab302571)

      Immunohistochemical analysis of 4% PFA-fixed, 0.2% Triton X-100 permeabilized frozen mouse cerebellum (fresh) tissue labeling PSD95 with ab302571 at 1/50 (10.0 μg/ml) dilution (Red). Image showing positive staining on mouse cerebellum. The nuclear counterstain was DAPI (Blue). Negative control: Primary diluent was used instead of primary antibody.

    • Immunohistochemistry (Frozen sections) - Alexa Fluor® 555 Anti-PSD95 antibody [EPR23124-118] - Synaptic Marker (ab302571)
      Immunohistochemistry (Frozen sections) - Alexa Fluor® 555 Anti-PSD95 antibody [EPR23124-118] - Synaptic Marker (ab302571)

      Immunohistochemical analysis of 4% PFA-fixed, 0.2% Triton X-100 permeabilized frozen rat cerebellum (fresh) tissue labeling PSD95 with ab302571 at 1/50 (10.0 μg/ml) dilution (Red). Image showing positive staining on rat cerebellum. The nuclear counterstain was DAPI (Blue). Negative control: Primary diluent was used instead of primary antibody.

    • Alexa Fluor® 555 Anti-PSD95 antibody [EPR23124-118] - Synaptic Marker (ab302571)
      Alexa Fluor® 555 Anti-PSD95 antibody [EPR23124-118] - Synaptic Marker (ab302571)

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab302571 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab302571 は論文での使用が確認できていません。

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