Alexa Fluor® 488 Anti-CD147 抗体 [MEM-M6/1], prediluted (ab187600)
![Flow Cytometry - Alexa Fluor® 488 Anti-CD147 antibody [MEM-M6/1], prediluted (ab187600)](https://www.abcam.co.jp/ps/products/187/ab187600/Images/ab187600-284956-anti-cd147-antibody-mem-m6-1-prediluted-alexa-fluor-488-flow-cytometry.jpg "Flow Cytometry - Alexa Fluor® 488 Anti-CD147 antibody [MEM-M6/1], prediluted (ab187600)")
Key features and details
- Alexa Fluor® 488 Mouse monoclonal [MEM-M6/1] to CD147, prediluted
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: Alexa Fluor® 488. Ex: 495nm, Em: 519nm
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
Alexa Fluor® 488 Anti-CD147 antibody [MEM-M6/1], prediluted
CD147 一次抗体 製品一覧 -
製品の詳細
Alexa Fluor® 488 Mouse monoclonal [MEM-M6/1] to CD147, prediluted -
由来種
Mouse -
標識
Alexa Fluor® 488. Ex: 495nm, Em: 519nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment corresponding to Human CD147 (Hinge). Protein A-CR purified soluble recombinant form of CD147, CD147Rg, consisting of cDNA coding for the hinge region, CH2 and CH3 domain of Human IgG1. (CD147Rg is secreted by transfectants as a dimer).
Database link: P35613 -
エピトープ
ab187600 recognizes an epitope in the N-terminal Ig domain (D1) of CD147. -
特記事項
ab187600 is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Store In the Dark. -
バッファー
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: 99% PBS, 0.2% BSA -
Concentration information loading... -
精製度
Size exclusion -
特記事項（精製）
Purified antibody is conjugated with Alexa Fluor® 488 under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary. -
ポリ/モノ
モノクローナル -
クローン名
MEM-M6/1 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab187600の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use 4µl for 106 cells.
(or 100 μl of whole blood). ab171463 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
| 特記事項 |
|---|
|
Flow Cyt
Use 4µl for 106 cells. (or 100 μl of whole blood). ab171463 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes. -
組織特異性
Present only in vascular endothelium in non-neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas. -
配列類似性
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
翻訳後修飾
N-glycosylated. -
細胞内局在
Cell membrane. Melanosome. Colocalizes with SLC16A1 and SLC16A8 (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV. - Information by UniProt
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参照データベース
- Entrez Gene: 682 Human
- Omim: 109480 Human
- SwissProt: P35613 Human
- Unigene: 501293 Human
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別名
- 5A11 antigen antibody
- 5F7 antibody
- BASI_HUMAN antibody
see all
画像
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Flow Cytometry - Alexa Fluor® 488 Anti-CD147 antibody [MEM-M6/1], prediluted (ab187600)
Flow cytometry analysis of human peripheral blood cells labelling CD147 with ab187600.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab187600 は 1 報の論文で使用されています。
- Koch C et al. T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density. Int Immunol 11:777-86 (1999). PubMed: 10330283
