Anti-ALDH1A1 抗体 (ab9883)
Key features and details
- Goat polyclonal to ALDH1A1
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-ALDH1A1 antibody
ALDH1A1 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to ALDH1A1 -
由来種
Goat -
特異性
This antibody may cross-react with ALDH1A2 (GeneID 8854) with one residue difference from this design, and with ALDH2 (GeneID 217) with two residues difference from this design. Please note that ALDH1A2 is known to be alternatively spliced under some conditions (37kDa).
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アプリケーション
適用あり: WBmore details
適用なし: ICC -
種交差性
交差種: Mouse, Rat, Human
交差が予測される動物種: Cow
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免疫原
Synthetic peptide: EVKTVTVKISQKNS, corresponding to C terminal amino acids 488-501 of Human Aldehyde Dehydrogenase 1.
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特記事項
A protease inhibitor that inhibits fibrin clot formation.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
一次抗体 備考
A protease inhibitor that inhibits fibrin clot formation. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab9883の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (2) |
Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 55 kDa.
1 hour primary incubation is recommended for this product. |
| 特記事項 |
|---|
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WB
Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 55 kDa. 1 hour primary incubation is recommended for this product. |
ターゲット情報
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機能
Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid. -
パスウェイ
Cofactor metabolism; retinol metabolism. -
配列類似性
Belongs to the aldehyde dehydrogenase family. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 281615 Cow
- Entrez Gene: 216 Human
- Entrez Gene: 11668 Mouse
- Entrez Gene: 24188 Rat
- Omim: 100640 Human
- SwissProt: P48644 Cow
- SwissProt: P00352 Human
- SwissProt: P24549 Mouse
see all -
別名
- Acetaldehyde dehydrogenase 1 antibody
- AHD2 antibody
- AL1A1_HUMAN antibody
see all
画像
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Western blot - Anti-ALDH1A1 antibody (ab9883)All lanes : Anti-ALDH1A1 antibody (ab9883) at 0.3 µg/ml
Lane 1 : Human liver lysate (protein in RIPA buffer)
Lane 2 : Rat liver lysate (protein in RIPA buffer)
Lane 3 : Mouse liver lysate (protein in RIPA buffer)
Lysates/proteins at 35 µg per lane.
Predicted band size: 55 kDaDetected by chemiluminescence.
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Western blot - Anti-ALDH1A1 antibody (ab9883)This image is courtesy of an anonymous AbreviewAnti-ALDH1A1 antibody (ab9883) at 1/500 dilution + MDBK cell lysate at 100 µg
Secondary
HRP-conjugated Donkey anti-goat IgG
Predicted band size: 55 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (20)
ab9883 は 20 報の論文で使用されています。
- Surmelioglu O et al. Predictive value of ALDH1 and CD44 positivity for radiotherapy response and prognosis in early-stage glottic laryngeal squamous cell carcinoma. Pol J Pathol 73:43-49 (2022). PubMed: 35848480
- Fernández-Pérez J et al. The effect of prior long-term recellularization with keratocytes of decellularized porcine corneas implanted in a rabbit anterior lamellar keratoplasty model. PLoS One 16:e0245406 (2021). PubMed: 34061862
- Sharaf K et al. Discrimination of Cancer Stem Cell Markers ALDH1A1, BCL11B, BMI-1, and CD44 in Different Tissues of HNSCC Patients. Curr Oncol 28:2763-2774 (2021). PubMed: 34287293
- Flori L et al. Development of Fortified Citrus Olive Oils: From Their Production to Their Nutraceutical Properties on the Cardiovascular System. Nutrients 12:N/A (2020). PubMed: 32471156
- Macaluso M et al. By-Products from Winemaking and Olive Mill Value Chains for the Enrichment of Refined Olive Oil: Technological Challenges and Nutraceutical Features. Foods 9:N/A (2020). PubMed: 33019655