AB137885

Anti-Albumin 抗体 [EPSISR1]

Anti-Albumin antibody [EPSISR1]

20ul selling size
RabMAb
Recombinant
Lab Essentials
詳細を見る

Be the first to review this product! Submit a review

(11 Publications)

Rabbit Recombinant Monoclonal Albumin antibody. Suitable for WB and reacts with Human samples. Cited in 11 publications.

別名を表示する

GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341, ALB, Albumin

2 Images

Unknown

Western blot - Anti-Albumin antibody [EPSISR1] (AB137885)

Blocking/Diluting buffer : 5% NFDM/TBST

All lanes:

Western blot - Anti-Albumin antibody [EPSISR1] (ab137885) at 1/10000 dilution

All lanes:

Human liver lysate at 15 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG (HRP) with minimal cross-reactivity with human IgG at 1/2000 dilution

Predicted band size: 69 kDa

Observed band size: 68 kDa

false

Unknown

Western blot - Anti-Albumin antibody [EPSISR1] (AB137885)

All lanes:

Western blot - Anti-Albumin antibody [EPSISR1] (ab137885) at 1/1000 dilution

Lane 1:

Human serum lysate at 10 µg

Lane 2:

Human fetal liver lysate at 10 µg

Secondary

All lanes:

HRP labelled goat anti-rabbit at 1/2000 dilution

Predicted band size: 69 kDa

false

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPSISR1

アイソタイプ

IgG

キャリアフリー

交差種

Human

アプリケーション

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/10000", "WB-species-notes": "<p><strong>For unpurified use at 1/1000 - 1/10000.</strong></p>" } } }

style

left-column

製品の詳細

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

style

left-column

出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Protein A

バッファー組成

Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

style

left-column

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Albumin also known as ALB is a major plasma protein with a molecular mass of approximately 66.5 kDa. It predominantly gets synthesized in the liver and found abundantly in blood plasma. Albumin serves multiple functions including maintaining osmotic pressure and acting as a carrier protein for various endogenous substances like hormones fatty acids and bilirubin.

Biological function summary

Albumin plays a critical role in transporting small molecules like metabolites and drugs through the circulatory system. It is not a part of any complex but functions independently to bind transport and release various ligands. Albumin's affinity for hydrophobic molecules makes it essential for they to be solubilized in blood for proper metabolism and excretion.

Pathways

More than five binding sites on albumin facilitate its role in the fatty acid metabolism and renin-angiotensin system pathways. In fatty acid metabolism albumin interacts with transport proteins carrying fatty acids to tissues for energy production. Additionally during the renin-angiotensin system albumin modulates blood pressure through its interaction with angiotensin II which can influence vasoconstriction.

Researchers link albumin with nephrotic syndrome and liver cirrhosis. In nephrotic syndrome low levels of albumin (albumin low) can cause edema due to imbalanced osmotic pressure. In liver cirrhosis a reduction in albumin synthesis signifies liver damage. Albumin's interaction with proteins like angiotensin II correlates with complications such as hypertension further establishing the protein's role in health and disease contexts.

style

left-column

style

left-column

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

ターゲットの情報

Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (PubMed : 19021548). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity). The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity). The rank order of affinity is zinc > calcium > magnesium (By similarity). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (PubMed : 6234017). Does not prevent iron uptake by the bacterial siderophore aerobactin (PubMed : 6234017).

See full target information ALB

style

left-column

文献 (11)

Recent publications for all applications. Explore the full list and refine your search

Developmental neuroscience 46:319-332 PubMed38190820

2024

Developmental Regulation of Matrix Metalloproteinases in Response to Multifactorial, Severe Traumatic Brain Injuries during Immaturity.

Applications

Unspecified application

Species

Unspecified reactive species

Alexandra Hochstetler,George Price,Amy Baohan,Melissa Li,Frances Rodriguez Lara,Josephine Lok,Beth Costine-Bartell

Acta biochimica et biophysica Sinica 55:601-612 PubMed37078751

2023

Adipose-derived stem cells show hepatic differentiation potential and therapeutic effect in rats with acute liver failure.

Applications

Unspecified application

Species

Unspecified reactive species

Yinpeng Jin,Rongfeng Shi,Tangkai Qi,Qiang Li,Cong Chen,Shane Gao,Fengjuan Gao,Danjing Yang,Guangxi Sun,Jianqing Xu,Qingchun Fu,Jun Xu,Xiaoyan Zhang

Pathogens (Basel, Switzerland) 9: PubMed32962019

2020

Uropathogens Preferrentially Interact with Conditioning Film Components on the Surface of Indwelling Ureteral Stents Rather than Stent Material.

Applications

Unspecified application

Species

Unspecified reactive species

Kymora B Scotland,Sonia Hy Kung,Ben H Chew,Dirk Lange

Nanoscale 12:15857-15868 PubMed32696774

2020

A method to measure the denatured proteins in the corona of nanoparticles based on the specific adsorption of Hsp90ab1.

Applications

Unspecified application

Species

Unspecified reactive species

Shang Liu,Xinbang Jiang,Xuejiao Tian,Zhenzhen Wang,Zhen Xing,Jiahui Chen,Junfeng Zhang,Chunming Wang,Lei Dong

Xenotransplantation 26:e12542 PubMed31219208

2019

Mesenchymal stem cells prolong survival and prevent lethal complications in a porcine model of fulminant liver failure.

Applications

Unspecified application

Species

Unspecified reactive species

Niang-Cheng Lin,Hao-Hsiang Wu,Jennifer Hui-Chun Ho,Chin-Su Liu,Oscar Kuang-Sheng Lee

Cell metabolism 30:329-342.e5 PubMed31204283

2019

Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Mitsukuni Yoshida,Akiko Satoh,Jonathan B Lin,Kathryn F Mills,Yo Sasaki,Nicholas Rensing,Michael Wong,Rajendra S Apte,Shin-Ichiro Imai

Nature protocols 14:1884-1925 PubMed31110298

2019

Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue.

Applications

Unspecified application

Species

Unspecified reactive species

Olivia C Tysoe,Alexander W Justin,Teresa Brevini,Si Emma Chen,Krishnaa T Mahbubani,Anna K Frank,Hajer Zedira,Espen Melum,Kourosh Saeb-Parsy,Athina E Markaki,Ludovic Vallier,Fotios Sampaziotis

Biomaterials 194:1-13 PubMed30562651

2018

Scanningless and continuous 3D bioprinting of human tissues with decellularized extracellular matrix.

Applications

Unspecified application

Species

Unspecified reactive species

Claire Yu,Xuanyi Ma,Wei Zhu,Pengrui Wang,Kathleen L Miller,Jacob Stupin,Anna Koroleva-Maharajh,Alexandria Hairabedian,Shaochen Chen

Journal of neurotrauma 36:815-833 PubMed30039743

2018

Development of a Model of Hemispheric Hypodensity ("Big Black Brain").

Applications

Unspecified application

Species

Unspecified reactive species

Beth A Costine-Bartell,Declan McGuone,George Price,Eleanor Crawford,Kristen L Keeley,Jennifer Munoz-Pareja,Carter P Dodge,Kevin Staley,Ann-Christine Duhaime

Tumour biology : the journal of the International 37:10943-58 PubMed26886287

2016

Combination of 5-fluorouracil and 2-morphilino-8-phenyl-4H-chromen-4-one may inhibit liver cancer stem cell activity.

Applications

Unspecified application

Species

Human

Yu-Chong Peng,Shi-Dong Lu,Jian-Hong Zhong,Zhi-Bo Xie,Xue-Mei You,Ning-Fu Peng,Le-Qun Li

View all publications

style

left-column

style

left-column

style

right-column

Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Albumin 抗体 [EPSISR1]

Anti-Albumin antibody [EPSISR1]

Western blot - Anti-Albumin antibody [EPSISR1] (AB137885)

Western blot - Anti-Albumin antibody [EPSISR1] (AB137885)

関連する標識済み抗体及び組成の異なる製品 (1)

Key facts

宿主種

クローン性

クローン番号

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

Reactivity data

製品の詳細

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

分注に関する情報

保管に関する情報

補足情報

Biological function summary

Pathways

製品プロトコール

ターゲットの情報

文献 (11)

代替製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

組合せ製品

Assay Kits

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Abcam product promise