Anti-AIPL1 抗体 (ab79039)
Key features and details
- Rabbit polyclonal to AIPL1
- Suitable for: WB, ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-AIPL1 antibody
AIPL1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to AIPL1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, ICC/IF, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
A 17 amino acid synthetic peptide near the carboxy terminus of human AIPL1 (NP_055151).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
ab79039 was purified by affinity chromatography via a peptide column -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab79039の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 44 kDa.
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| ICC/IF |
Use a concentration of 20 µg/ml.
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| IHC-P |
Use at an assay dependent concentration.
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| 特記事項 |
|---|
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 44 kDa. |
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ICC/IF
Use a concentration of 20 µg/ml. |
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IHC-P
Use at an assay dependent concentration. |
ターゲット情報
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機能
May be important in protein trafficking and/or protein folding and stabilization. -
組織特異性
Highly expressed in retina. Specifically localized to the developing photoreceptor layer and within the photoreceptors of the adult retina. -
関連疾患
Defects in AIPL1 are the cause of Leber congenital amaurosis type 4 (LCA4) [MIM:604393]. LCA designates a clinically and genetically heterogeneous group of childhood retinal degenerations, generally inherited in an autosomal recessive manner. Affected infants have little or no retinal photoreceptor function as tested by electroretinography. LCA represents the most common genetic cause of congenital visual impairment in infants and children. -
配列類似性
Contains 1 PPIase FKBP-type domain.
Contains 3 TPR repeats. -
細胞内局在
Cytoplasm. Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 23746 Human
- Omim: 604392 Human
- SwissProt: Q9NZN9 Human
- Unigene: 279887 Human
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別名
- A930007I01Rik antibody
- Aipl1 antibody
- AIPL1_HUMAN antibody
see all
画像
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Immunocytochemistry/ Immunofluorescence - Anti-AIPL1 antibody (ab79039)
Immunofluorescence of AIPL1 in Human brain tissue with ab79039 at 20 ug/mL.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AIPL1 antibody (ab79039)Immunohistochemistry of Human brain tisue using ab79039 at 2.5 μg/ml.
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Western blot - Anti-AIPL1 antibody (ab79039)Lane 1 : Anti-AIPL1 antibody (ab79039) at 1 µg/ml
Lane 2 : Anti-AIPL1 antibody (ab79039) at 2 µg/ml
All lanes : Human brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 44 kDa
Observed band size: 36 kDa why is the actual band size different from the predicted?
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab79039 は 1 報の論文で使用されています。
- He J et al. SIPL1, Regulated by MAZ, Promotes Tumor Progression and Predicts Poor Survival in Human Triple-Negative Breast Cancer. Front Oncol 11:766790 (2021). PubMed: 34976812