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AB112528

Anti-AHSG 抗体

Anti-AHSG antibody

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(5 Publications)

Rabbit Polyclonal FETUA antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human AHSG.

別名を表示する

FETUA, PRO2743, AHSG, Alpha-2-HS-glycoprotein, Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, Fetuin-A

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Human

アプリケーション

WB

applications

免疫原

Synthetic Peptide within Human AHSG. The exact immunogen used to generate this antibody is proprietary information.

P02765

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代替製品

Primary Antibodies

AB47979

Anti-AHSG antibody

Immunocytochemistry/ Immunofluorescence - Anti-AHSG antibody (AB47979)

  • 0
  • 0
Primary Antibodies

AB187051

Anti-AHSG antibody [EPR17839-163]

20ul selling size|RabMAb|Recombinant|Trial Size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AHSG antibody [EPR17839-163] (AB187051)

  • 0
  • 0
Primary Antibodies

AB118830

Anti-AHSG antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AHSG antibody (AB118830)

  • 0
  • 0
Primary Antibodies

AB226243

Anti-AHSG antibody [EPR17839-163] - BSA and Azide free

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AHSG antibody [EPR17839-163] - BSA and Azide free (AB226243)

  • 0
  • 0

組合せ製品

Assay Kits

AB108855

Human Fetuin A ELISA Kit (AHSG)

Sandwich ELISA - Human Fetuin A ELISA Kit (AHSG) (AB108855)

  • 0
  • 0
Primary Antibodies

AB207303

Anti-alpha 1 Antitrypsin antibody [EPR17087-50]

RabMAb|Recombinant|KO Validated|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-alpha 1 Antitrypsin antibody [EPR17087-50] (AB207303)

  • 4
  • 2
Primary Antibodies

AB181602

Anti-GAPDH antibody [EPR16891] - Loading Control

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GAPDH antibody [EPR16891] - Loading Control (AB181602)

  • 5
  • 23
Primary Antibodies

AB244758

Anti-IL-6 antibody [IL-6-10] - BSA and Azide free (Capture)

RabMAb|Recombinant

Sandwich ELISA - Anti-IL-6 antibody [IL-6-10] - BSA and Azide free (Capture) (AB244758)

  • 0
  • 0
Primary Antibodies

AB108252

Anti-ACE2 antibody [EPR4435(2)]

BOND RX™ Validated|RabMAb|Recombinant|KO Validated|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACE2 antibody [EPR4435(2)] (AB108252)

  • 4
  • 10
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p>The detection limit for Alpha 2 HS Glycoprotein is approximately 2.5ng/lane.under non-reducing and reducing conditions.</p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
Preservative: 0.025% Sodium azide, 0.025% Thimerosal (merthiolate) Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Disodium hydrogenorthophosphate
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

The target AHSG also known as fetuin-A or alpha-2-HS-glycoprotein is a multifunctional glycoprotein with an approximate mass of 64-68 kDa. It is mainly expressed in the liver and secreted into the bloodstream. AHSG exhibits a wide range of interactions with different cell types and biological molecules playing key roles in mineralization inhibition of arterial calcification and modulation of immune responses.
Biological function summary

AHSG protein serves multiple functions including acting as an inhibitor of insulin receptor autophosphorylation and serine-threonine kinase activities. AHSG is part of a complex dynamic process involving calcium metabolism and bone mineralization. It binds to transforming growth factor-beta (TGF-β) and other proteins modulating cellular signals and maintaining homeostasis in tissues. The regulation of calcium ion balance by AHSG can protect against ectopic calcification preventing potential damage.

Pathways

Calcium signaling and the insulin signaling pathways integrate AHSG functions. AHSG interacts with proteins like insulin receptor and those in the canonical Wnt signaling pathway influencing glucose metabolism and bone development. The balance of its interactions in these pathways helps maintain metabolic homeostasis and skeletal integrity reflecting its versatile roles within complex networks.

AHSG has connections to metabolic syndrome and calcific aortic valve disease. Abnormal levels of AHSG can disrupt metabolic functions and contribute to type 2 diabetes development by affecting insulin receptor activity. It also associates with calcification-related proteins in vascular tissues linking it to cardiovascular diseases. Understanding these connections is important for potential therapeutic targeting of AHSG in related pathologies.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.
See full target information AHSG
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文献 (5)

Recent publications for all applications. Explore the full list and refine your search

Journal of neuroinflammation 19:269 PubMed36333786

2022

Fetuin-A alleviates neuroinflammation against traumatic brain injury-induced microglial necroptosis by regulating Nrf-2/HO-1 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Pengzhan Zhao,Yutian Wei,Guangchi Sun,Lei Xu,Tian Wang,Yufei Tian,Honglu Chao,Yiming Tu,Jing Ji

Journal of cellular physiology 235:7604-7619 PubMed32437028

2020

Proteomic analysis of underlying apoptosis mechanisms of human retinal pigment epithelial ARPE-19 cells in response to mechanical stretch.

Applications

Unspecified application

Species

Unspecified reactive species

Fancheng Yan,Meng Gao,Yiyi Gong,Lin Zhang,Nanping Ai,Jingxue Zhang,Yijie Chai,Shen Wu,Qian Liu,Xian Jiang,Haiteng Deng,Wu Liu

Biomolecules 10: PubMed32260542

2020

Tick and Host Derived Compounds Detected in the Cement Complex Substance.

Applications

Unspecified application

Species

Unspecified reactive species

Margarita Villar,Iván Pacheco,Octavio Merino,Marinela Contreras,Lourdes Mateos-Hernández,Eduardo Prado,Dina Karen Barros-Picanço,José Francisco Lima-Barbero,Sara Artigas-Jerónimo,Pilar Alberdi,Isabel G Fernández de Mera,Agustín Estrada-Peña,Alejandro Cabezas-Cruz,José de la Fuente

PloS one 12:e0186227 PubMed29016670

2017

A novel function of N-linked glycoproteins, alpha-2-HS-glycoprotein and hemopexin: Implications for small molecule compound-mediated neuroprotection.

Applications

Unspecified application

Species

Unspecified reactive species

Takuya Kanno,Kaori Yasutake,Kazunori Tanaka,Shinji Hadano,Joh-E Ikeda

BioMed research international 2015:209745 PubMed26448929

2015

Plasma Protein Biomarker Candidates for Myelodysplastic Syndrome Subgroups.

Applications

Unspecified application

Species

Unspecified reactive species

Pavel Majek,Klara Pecankova,Jaroslav Cermak,Jan E Dyr
View all publications
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